发明申请
- 专利标题： PROCESS FOR PREPARING PRAVASTATIN
- 专利标题（中）： 制备PRAVASTATIN的方法
-
申请号： US12518713申请日： 2007-12-11
-
公开(公告)号： US20100217032A1公开(公告)日： 2010-08-26
- 发明人: Paul Klaassen , Adrianus Wilhelmus Hermanus Vollebregt , Marco Alexander Van Den Berg , Marcus Hans , Jan Metske Van Der Laan
- 申请人： Paul Klaassen , Adrianus Wilhelmus Hermanus Vollebregt , Marco Alexander Van Den Berg , Marcus Hans , Jan Metske Van Der Laan
- 优先权： EP06126046.9 20061213
- 国际申请： PCT/EP07/63638 WO 20071211
- 主分类号： C12P7/62
- IPC分类号： C12P7/62 ; C07K14/195 ; C07H21/04 ; C07C69/34
摘要：
The present invention provides a polypeptide having an amino acid sequence according to SEQ ID NO 3, SEQ ID NO 6 or SEQ ID NO 43-59. The present invention also provides a polynucleotide comprising a DNA sequence encoding these polypeptides and a method for isolating polynucleotides encoding polypeptides capable of improving the compactin into pravastatin conversion. Furthermore, the present invention provides a method for producing pravastatin and a pharmaceutical composition comprising pravastatin.
信息查询
