摘要:
The present invention provides a polypeptide having an amino acid sequence according to SEQ ID NO 3, SEQ ID NO 6 or SEQ ID NO 43-59. The present invention also provides a polynucleotide comprising a DNA sequence encoding these polypeptides and a method for isolating polynucleotides encoding polypeptides capable of improving the compactin into pravastatin conversion. Furthermore, the present invention provides a method for producing pravastatin and a pharmaceutical composition comprising pravastatin.
摘要翻译:本发明提供具有根据SEQ ID NO 3,SEQ ID NO 6或SEQ ID NO 43-59的氨基酸序列的多肽。 本发明还提供了一种包含编码这些多肽的DNA序列的多核苷酸,以及一种分离编码多肽的方法,所述多核苷酸能够将该致密蛋白改进普伐他汀转化。 此外,本发明提供了普伐他汀的制造方法和含有普伐他汀的药物组合物。
摘要:
The invention relates to a Talaromyces transformant comprising one or more recombinant gene, capable of producing cellulase in the absence of cellulase inducer in a glucose medium, having a cellulase activity of 2 WSU/ml or more, in 16 times or more diluted supernatant or broth.
摘要:
The present invention relates to Talaromyces strains. The invention further relates to enzyme compositions, which may be produced by the Talaromyces strains. Further the invention relates to methods for producing useful products from lignocellulosic material using the enzyme compositions.
摘要:
The present invention discloses a process for the production of N-deacylated cephalosporin compounds via the fermentative production of their 7-acylated counterparts.
摘要:
A process is taught for the preparation and recovery of 7-aminodesacetoxycephalosporanic acid (7-ADCA) via enzymatic ring expansion activity on penicillin G, using a Penicillium chrysogenum transformant strain expressing expandase.
摘要:
The present invention discloses a method for the preservation of beverages comprising the use of a killer toxin. Specifically, zymocin is used in carbonated drinks. The zymocin is shown to be active against a wide range of different yeast strains. The invention further discloses a DNA fragment encoding zymocin. The DNA sequence is also disclosed.
摘要:
The invention relates to a Talaromyces transformant comprising one or more recombinant gene, capable of producing cellulase in the absence of cellulase inducer in a glucose medium, having a cellulase activity of 2 WSU/ml or more, in 16 times or more diluted supernatant or broth.
摘要:
The present invention disclosures a process for the production of N-deacylated cephalosporin compounds via the fermentative production of their 7-acylated counterparts.