发明申请
- 专利标题: APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
- 专利标题(中): 用于治疗癌症和免疫和自发性疾病的病毒诱导剂
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申请号: US12793413申请日: 2010-06-03
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公开(公告)号: US20100298323A1公开(公告)日: 2010-11-25
- 发明人: Milan Bruncko , Yujia Dai , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura Hexamer , Aaron R. Kunzer , Robert A. Mantei , William J. McClellan , Chang H. Park , Cheol-Min Park , Andrew M. Petros , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt , Todd M. Hansen
- 申请人: Milan Bruncko , Yujia Dai , Hong Ding , George A. Doherty , Steven W. Elmore , Lisa Hasvold , Laura Hexamer , Aaron R. Kunzer , Robert A. Mantei , William J. McClellan , Chang H. Park , Cheol-Min Park , Andrew M. Petros , Xiaohong Song , Andrew J. Souers , Gerard M. Sullivan , Zhi-Fu Tao , Gary T. Wang , Le Wang , Xilu Wang , Michael D. Wendt , Todd M. Hansen
- 申请人地址: US IL Abbott Park
- 专利权人: ABBOTT LABORATORIES
- 当前专利权人: ABBOTT LABORATORIES
- 当前专利权人地址: US IL Abbott Park
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D405/12 ; C07D405/14 ; C07D413/14 ; C07D413/12 ; C07D295/155 ; C07D403/14 ; C07D401/12 ; C07D417/14 ; A61K31/5377 ; A61K31/495 ; A61P35/00 ; A61P35/02
摘要:
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.