发明申请
US20130035310A1 Piperidine and Piperazine Phenyl Sulfonamides as Modulators of Ion Channels
有权
哌啶和哌嗪苯磺酰胺作为离子通道的调节剂
- 专利标题: Piperidine and Piperazine Phenyl Sulfonamides as Modulators of Ion Channels
- 专利标题(中): 哌啶和哌嗪苯磺酰胺作为离子通道的调节剂
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申请号: US13633478申请日: 2012-10-02
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公开(公告)号: US20130035310A1公开(公告)日: 2013-02-07
- 发明人: Esther Ann Martinborough , Lev Tyler Dewey Fanning , Urvi Jagdishbhai Sheth , Dean Mitchell Wilson , Andreas P. Termin , Timothy Donald Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson
- 申请人: Esther Ann Martinborough , Lev Tyler Dewey Fanning , Urvi Jagdishbhai Sheth , Dean Mitchell Wilson , Andreas P. Termin , Timothy Donald Neubert , Nicole Hilgraf , Tara Leanne Hampton , Tara Whitney , Aarti Sameer Kawatkar , Danielle Lehsten , Dean Stamos , Jinglan Zhou , Vijayalaksmi Arumugam , Corey Anderson
- 申请人地址: US MA Cambridge
- 专利权人: VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人: VERTEX PHARMACEUTICALS INCORPORATED
- 当前专利权人地址: US MA Cambridge
- 主分类号: A61K31/635
- IPC分类号: A61K31/635 ; A61K31/454 ; A61K31/4545 ; A61K31/496 ; A61K31/427 ; A61K31/695 ; A61P29/00 ; A61P25/06 ; A61P25/00 ; A61P25/22 ; A61P25/24 ; A61P25/08 ; A61P9/06 ; A61P25/28 ; A61P19/02 ; A61P9/12 ; A61P1/00 ; A61K31/506
摘要:
The present invention relates to piperidine and piperazine phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain.
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