- 专利标题: BORON-CONTAINING SMALL MOLECULES
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申请号: US13607250申请日: 2012-09-07
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公开(公告)号: US20130059802A1公开(公告)日: 2013-03-07
- 发明人: Stephen J. Baker , Tsutomu Akama , Michael Richard Kevin Alley , Stephen J. Benkovic , Michael DiPierro , Vincent S. Hernandez , Karin M. Hold , Isaac Kennedy , Igor Likhotvorik , Weimin Mao , Kirk R. Maples , Jacob J. Plattner , Fernando Rock , Virginia Sanders , Aaron M. Stemphoski , George Petros Yiannikouros , Siead Zagar , Yong-Kang Zhang , Huchen Zhou
- 申请人: Stephen J. Baker , Tsutomu Akama , Michael Richard Kevin Alley , Stephen J. Benkovic , Michael DiPierro , Vincent S. Hernandez , Karin M. Hold , Isaac Kennedy , Igor Likhotvorik , Weimin Mao , Kirk R. Maples , Jacob J. Plattner , Fernando Rock , Virginia Sanders , Aaron M. Stemphoski , George Petros Yiannikouros , Siead Zagar , Yong-Kang Zhang , Huchen Zhou
- 申请人地址: US CA Palo Alto
- 专利权人: Anacor Pharmaceuticals, Inc.
- 当前专利权人: Anacor Pharmaceuticals, Inc.
- 当前专利权人地址: US CA Palo Alto
- 主分类号: A61K31/69
- IPC分类号: A61K31/69 ; A61P31/10 ; A61K31/7034 ; A61K31/7024 ; A61K31/7076
摘要:
This invention relates to compounds useful for treating fungal infections, more specifically topical treatment of onychomycosis and/or cutaneous fungal infections. This invention is directed to compounds that are active against fungi and have properties that allow the compound, when placed in contact with a patient, to reach the particular part of the skin, nail, hair, claw or hoof infected by the fungus. In particular the present compounds have physiochemical properties that facilitate penetration of the nail plate.
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