- 专利标题： ENZYMATIC CONJUGATION OF POLYPEPTIDES
-
申请号： US15654585申请日： 2017-07-19
-
公开(公告)号： US20180071402A1公开(公告)日： 2018-03-15
- 发明人: Delphine Bregeon , Patrick Dennler , Christian Belmant , Eliane Fischer , Laurent Gauthier , Francois Romagné , Roger Schibli
- 申请人： Innate Pharma , Paul Scherrer Institut
- 主分类号： G01N33/68
- IPC分类号： G01N33/68 ; C12N9/10 ; C12P21/00 ; C07K19/00 ; C07K16/00 ; C07F9/50 ; C07D277/06 ; C07D257/08 ; C07D225/08 ; C07C323/60 ; C07C323/12 ; C07C247/04 ; C07C233/62 ; C07C229/26 ; C07C223/02 ; C07C217/08
摘要：
The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.