Invention Application
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS AND METHODS AND USES THEREFOR](/docs/US/2020-02-06/US20200038403A1/abs.jpg.600x600.jpg)
- Patent Title: 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS AND METHODS AND USES THEREFOR
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Application No.: US16527802Application Date: 2019-07-31
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Publication No.: US20200038403A1Publication Date: 2020-02-06
- Inventor: Yam B. POUDEL , Sanjeev GANGWAR , Liqi HE , Prasanna SIVAPRAKASAM , Matthias BROEKEMA , Matthew COX , Christine M. TARBY , Qian ZHANG
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04 ; A61K39/395 ; A61K47/60
![1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS AND METHODS AND USES THEREFOR](/abs-image/US/2020/02/06/US20200038403A1/abs.jpg.150x150.jpg)
Abstract:
Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.
Public/Granted literature
Information query
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