- 专利标题： KRAS G12C INHIBITORS AND METHODS OF USING THE SAME
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申请号： US17579359申请日： 2022-01-19
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公开(公告)号： US20220175782A1公开(公告)日： 2022-06-09
- 发明人: John Gordon ALLEN , Brian Alan LANMAN , Jian CHEN , Anthony B. REED , Victor J. CEE , Longbin LIU , Patricia LOPEZ , Ryan Paul WURZ , Thomas T. NGUYEN , Shon BOOKER , Jennifer Rebecca ALLEN , Margaret CHU-MOYER , Albert AMEGADZIE , Ning CHEN , Clifford GOODMAN , Jonathan D. LOW , Vu Van MA , Ana Elena MINATTI , Nobuko NISHIMURA , Alexander J. PICKRELL , Hui-Ling WANG , Youngsook SHIN , Aaron C. SIEGMUND , Kevin C. YANG , Nuria A. TAMAYO , Mary WALTON , Qiufen XUE
- 申请人： AMGEN INC.
- 申请人地址： US CA Thousand Oaks
- 专利权人： AMGEN INC.
- 当前专利权人： AMGEN INC.
- 当前专利权人地址： US CA Thousand Oaks
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/551 ; A61K39/395 ; A61P35/00
摘要：
Provided herein are KRAS G12C inhibitors, such as composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.
公开/授权文献
- US12083121B2 Substituted piperazines as KRAS G12C inhibitors 公开/授权日：2024-09-10
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