Invention Application
- Patent Title: METHOD FOR REGENERATION OF AN OVERLOAD CHROMATOGRAPHY COLUMN
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Application No.: US17542138Application Date: 2021-12-03
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Publication No.: US20220203347A1Publication Date: 2022-06-30
- Inventor: Marc L. Wong , Donna F. Quicho , Jason A. Brown , Josefine K. Persson , Amy Lim
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: B01J49/53
- IPC: B01J49/53 ; B01J41/20 ; B01J49/07 ; B01J49/57 ; C07K1/18 ; B01J49/06 ; B01J39/26 ; B01D15/36 ; B01D15/20 ; B01D15/42 ; B01D15/38

Abstract:
The present invention provides methods for cleaning or regenerating a chromatography material for reuse. The methods of the invention can be used for cleaning or regenerating ion exchange chromatography columns for reuse in the large-scale manufacture of multiple polypeptide products where the ion exchange chromatography column in used in overload mode.
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