Invention Publication
- Patent Title: mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS
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Application No.: US18481797Application Date: 2023-10-05
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Publication No.: US20240228636A1Publication Date: 2024-07-11
- Inventor: Barbara Johnson SASU , Arvind RAJPAL , Philippe DUCHATEAU , Alexandre JUILLERAT , Julien VALTON
- Applicant: Cellectis , Allogene Therapeutics, Inc.
- Applicant Address: FR CA Paris
- Assignee: Cellectis,Allogene Therapeutics, Inc.
- Current Assignee: Cellectis,Allogene Therapeutics, Inc.
- Current Assignee Address: FR CA Paris
- Priority: DK 20157004 2015.01.26
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K35/17 ; A61K39/00 ; A61K39/395 ; C07K14/705 ; C07K14/725 ; C07K14/735 ; C07K16/30 ; C12N5/00 ; C12N5/0783 ; G01N15/01 ; G01N15/10 ; G01N15/1031 ; G01N15/14 ; G01N15/149
Abstract:
A polypeptide encoding a chimeric antigen receptor (CAR) comprising at least one extracellular binding domain that comprises a scFv formed by at least a VH chain and a VL chain specific to an antigen, wherein said extracellular binding domain comprises at least one mAb-specific epitope.
Information query
