发明授权
- 专利标题： Method for determining the presence of malignant cells
- 专利标题（中）： 确定恶性细胞存在的方法
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申请号： US595073申请日： 1984-03-30
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公开(公告)号： US4782015A公开(公告)日： 1988-11-01
- 发明人: Anthony C. Allison , Vera Morhenn , Alain B. Schreiber
- 申请人： Anthony C. Allison , Vera Morhenn , Alain B. Schreiber
- 申请人地址： CA Palo Alto
- 专利权人： Syntex (U.S.A.) Inc.
- 当前专利权人： Syntex (U.S.A.) Inc.
- 当前专利权人地址： CA Palo Alto
- 主分类号： G01N33/574
- IPC分类号： G01N33/574 ; A61K39/395 ; C07K14/005 ; C07K14/195 ; C07K16/00 ; C07K16/30 ; C07K19/00 ; C12N5/10 ; C12N15/02 ; C12P21/08 ; C12R1/91 ; G01N33/577
摘要：
The present invention is concerned with a method for determining the presence of a malignant condition at a locus of interest. An exfoliative cell specimen obtained from the locus is contacted with an antibody specific for an antigenic site that is usually only found in the specimen when a malignant condition is present. The contact is made under conditions for detectable binding of the antibody to such antigenic site. After contact, the presence of binding of the antibody to the antigenic site is observed. The binding of the antibody is related to the presence of a malignant condition at the locus. The invention finds utility, for example, in the detection of cervical carcinoma.
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