发明授权
- 专利标题: Renin inhibitors and aminoacid and aminoaldehyde derivatives
- 专利标题(中): 肾素抑制剂和氨基酸和氨基醛衍生物
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申请号: US22710申请日: 1987-03-06
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公开(公告)号: US4818748A公开(公告)日: 1989-04-04
- 发明人: Wolfgang Bender , Rolf Henning , Andreas Knorr , Johannes-Peter Stasch
- 申请人: Wolfgang Bender , Rolf Henning , Andreas Knorr , Johannes-Peter Stasch
- 申请人地址: DEX Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DEX Leverkusen
- 优先权: DEX3608209 19860312; DEX3628650 19860823
- 主分类号: C07K14/81
- IPC分类号: C07K14/81 ; A61K38/00 ; A61K38/55 ; A61P9/12 ; C07C67/00 ; C07C223/06 ; C07C229/22 ; C07C231/00 ; C07C233/36 ; C07C233/43 ; C07C237/02 ; C07C237/06 ; C07C237/12 ; C07C237/22 ; C07C239/00 ; C07C253/00 ; C07C255/58 ; C07C255/59 ; C07C269/00 ; C07C273/10 ; C07C301/00 ; C07C303/30 ; C07C303/40 ; C07C311/00 ; C07D233/54 ; C07D249/08 ; C07D521/00 ; C07K20060101 ; C07K1/00 ; C07K1/113 ; C07K5/02 ; C07K5/06 ; C07K5/08 ; C07K5/10 ; C07K7/02 ; A61K37/02 ; C07K7/06
摘要:
Anti-hypertensive compounds of the formula ##STR1## in which A represents hydrogen, C.sub.1 -C.sub.8 -alkyl, C.sub.7 -C.sub.14 -aralkyl, phenylsulphonyl, tolylsulphonyl or C.sub.1 -C.sub.8 -alkylsulfphonyl, or represents an aminoprotective group,B represents a direct bond, or represents sarcosyl, or represents a group of the formula ##STR2## D represents a direct bond, or represents a group of the formula ##STR3## wherein X represents methylene, ethylene or sulphur,E, G, J, K, L and M independently have the same meanings as B,R.sup.1 is an optionally substituted phenyl radical, andQ is a hydroxy, alkoxy or amino group, or a physiologically acceptable salt thereof.
公开/授权文献
- US6146121A Rotor for use in a rotary pump 公开/授权日:2000-11-14
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