发明授权
- 专利标题： Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents
- 专利标题（中）： 碳环稠环喹啉羧酸可用作免疫抑制剂
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申请号： US114712申请日： 1993-08-31
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公开(公告)号： US5428040A公开(公告)日： 1995-06-27
- 发明人: Ronald L. Magolda , William J. Pitts , Irina C. Jacobson , Carl H. Behrens , Michael J. Orwat , Douglas G. Batt
- 申请人： Ronald L. Magolda , William J. Pitts , Irina C. Jacobson , Carl H. Behrens , Michael J. Orwat , Douglas G. Batt
- 申请人地址： DE Wilmington
- 专利权人： The Du Pont Merck Pharmaceutical Company
- 当前专利权人： The Du Pont Merck Pharmaceutical Company
- 当前专利权人地址： DE Wilmington
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A61K31/473 ; A61K31/4738 ; A61P29/00 ; A61P37/00 ; A61P37/06 ; C07D221/18 ; C07D405/04 ; C07D409/04 ; C07D471/04 ; C07D487/14 ; C07D491/04 ; C07D491/048 ; C07D491/052 ; C07D491/147 ; C07D495/04 ; C07D495/14 ; A61K31/435 ; C07D215/02
摘要：
This invention relates to carbocyclic and heterocyclic fused-ring quinolinecarboxylic acid compounds, to pharmaceutical compositions comprising such compounds, and to methods of using such compounds for the treatment and/or prevention of organ transplantation rejection, graft versus host disease, autoimmune diseases, chronic inflammatory diseases, including but not limited to psoriasis and rheumatoid arthritis, and cancer in a mammal.
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