发明授权
US5686486A 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl�b!pyran-2-ones
useful to treat retroviral infections
失效
可用于治疗逆转录病毒感染的4-羟基 - 苯并吡喃-2-酮和4-羟基 - 环烷基[b]吡喃-2-酮
- 专利标题: 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl�b!pyran-2-ones useful to treat retroviral infections
- 专利标题(中): 可用于治疗逆转录病毒感染的4-羟基 - 苯并吡喃-2-酮和4-羟基 - 环烷基[b]吡喃-2-酮
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申请号: US492068申请日: 1995-08-04
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公开(公告)号: US5686486A公开(公告)日: 1997-11-11
- 发明人: Paul Kosta Tomich , Michael John Bohanon , Steven Ronald Turner , Joseph Walter Strohbach , Suvit Thaisrivongs , Richard C. Thomas , Karen Rene Romines , Chih-Ping Yang , Paul Adrian Aristoff , Harvey Irving Skulnick , Paul D. Johnson , Ronald B. Gammill , Qingwei Zhang , Gordon L. Bundy , David John Anderson , Lee S. Banitt
- 申请人: Paul Kosta Tomich , Michael John Bohanon , Steven Ronald Turner , Joseph Walter Strohbach , Suvit Thaisrivongs , Richard C. Thomas , Karen Rene Romines , Chih-Ping Yang , Paul Adrian Aristoff , Harvey Irving Skulnick , Paul D. Johnson , Ronald B. Gammill , Qingwei Zhang , Gordon L. Bundy , David John Anderson , Lee S. Banitt
- 申请人地址: MI Kalamazoo
- 专利权人: Pharmacia & Upjohn Company
- 当前专利权人: Pharmacia & Upjohn Company
- 当前专利权人地址: MI Kalamazoo
- 主分类号: C07D311/46
- IPC分类号: C07D311/46 ; A61K31/352 ; A61K31/365 ; A61K31/37 ; A61K31/38 ; A61K31/381 ; A61K31/40 ; A61K31/4035 ; A61K31/404 ; A61K31/415 ; A61K31/4178 ; A61K31/4184 ; A61K31/427 ; A61K31/4433 ; A61K31/453 ; A61K31/4709 ; A61K31/496 ; A61K31/5377 ; A61P31/12 ; A61P31/18 ; A61P43/00 ; C07D311/54 ; C07D311/56 ; C07D311/74 ; C07D311/92 ; C07D311/94 ; C07D405/04 ; C07D405/12 ; C07D407/06 ; C07D407/08 ; C07D409/06 ; C07D409/08 ; C07D409/12 ; C07D413/12 ; C07D417/10 ; C07D417/12 ; A61K31/35 ; C07D311/20
摘要:
The present invention relates to compounds of formula I which are 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl�b!pyran-2-ones useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus. ##STR1## Wherein R.sub.10 and R.sub.20 taken together are: ##STR2##
公开/授权文献
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