发明授权
- 专利标题： Cycloalkyl tachykinin receptor antagonists
- 专利标题（中）： 环烷基速激肽受体拮抗剂
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申请号： US730277申请日： 1996-10-15
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公开(公告)号： US5750549A公开(公告)日： 1998-05-12
- 发明人: Charles G. Caldwell , Ping Chen , Philippe L. Durette , Paul Finke , Jeffrey Hale , Edward Holson , Ihor Kopka , Malcolm MacCoss , Laura Meurer , Sander G. Mills , Albert Robichaud
- 申请人： Charles G. Caldwell , Ping Chen , Philippe L. Durette , Paul Finke , Jeffrey Hale , Edward Holson , Ihor Kopka , Malcolm MacCoss , Laura Meurer , Sander G. Mills , Albert Robichaud
- 申请人地址： NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： NJ Rahway
- 主分类号： C07C69/757
- IPC分类号： C07C69/757 ; C07C217/52 ; C07C237/06 ; C07C255/59 ; C07D207/08 ; C07D207/16 ; C07D207/26 ; C07D213/30 ; C07D213/38 ; C07D213/61 ; C07D215/18 ; C07D215/20 ; C07D233/70 ; C07D239/26 ; C07D249/08 ; C07D249/12 ; C07D257/04 ; C07D261/08 ; C07D271/06 ; C07D271/10 ; C07D277/28 ; C07D277/64 ; C07D307/12 ; C07D307/82 ; C07D333/20 ; C07D333/32 ; C07D333/64 ; C07D401/04 ; C07D403/12 ; C07D405/12 ; C07D413/12 ; C07D417/04 ; C07D417/12 ; C07D513/04 ; C07D521/00 ; A61K31/41
摘要：
The present invention is directed to certain novel compounds represented by structural formula I: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, Q, W, X, Y, Z and n are defined herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are tachykinin receptor antagonists and are useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis.
公开/授权文献
- US5226726A Foldable lantern frame 公开/授权日：1993-07-13
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