发明授权
- 专利标题: Amine derivatives for treatment of skin disorders
- 专利标题(中): 用于治疗皮肤病的胺衍生物
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申请号: US817928申请日: 1997-05-30
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公开(公告)号: US5801202A公开(公告)日: 1998-09-01
- 发明人: Taketoshi Fujimori , Hiroshi Kusuoku , Akira Yamamuro , Yukihiro Yada , Kazuhiko Higuchi , Genji Imokawa , Naoki Kondo , Yoshinori Masukawa , Hajime Tokuda , Hisashi Tsujimura
- 申请人: Taketoshi Fujimori , Hiroshi Kusuoku , Akira Yamamuro , Yukihiro Yada , Kazuhiko Higuchi , Genji Imokawa , Naoki Kondo , Yoshinori Masukawa , Hajime Tokuda , Hisashi Tsujimura
- 申请人地址: JPX Tokyo
- 专利权人: Kao Coproration
- 当前专利权人: Kao Coproration
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX6-274874 19941109; JPX6-274875 19941109
- 主分类号: A61K8/41
- IPC分类号: A61K8/41 ; A61K31/13 ; A61Q19/00 ; C07C217/28 ; C07D303/22 ; A01K31/13
摘要:
Disclosed is an amine derivative represented by the following formula (1) or an acid addition salt thereof: ##STR1## wherein R.sup.1 represents a group ##STR2## a cyclopentyl group, cyclohexyl group, or a cycloheptyl group, R.sup.2 is a hydrogen atom or C1-C3 alkyl group which may be substituted by one or more hydroxyl groups, m is an integer falling in the range from 3 to 5 inclusive, and n is an integer falling in the range from 9 to 11 inclusive. Also, intermediates useful in the manufacture of the amine derivative (1), compositions for external application to the skin containing the amine derivative, and keratinization improvers containing the amine derivative as an active component are described. The compound (1) has excellent keratinization improving action, pigmentation preventing action, etc.
公开/授权文献
- US5154840A Environmentally friendly grease compositions 公开/授权日:1992-10-13
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