- 专利标题: Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule
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申请号: US483316申请日: 1995-06-07
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公开(公告)号: US06045802A公开(公告)日: 2000-04-04
- 发明人: Jeffrey Schlom , Judith Kantor , James W. Hodge
- 申请人: Jeffrey Schlom , Judith Kantor , James W. Hodge
- 申请人地址: DC Washington
- 专利权人: The United States of America as represented by the Secretary of the Department Of Health and Human Services
- 当前专利权人: The United States of America as represented by the Secretary of the Department Of Health and Human Services
- 当前专利权人地址: DC Washington
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K35/74 ; A61K35/76 ; A61K38/00 ; A61K39/00 ; A61K39/002 ; A61K39/02 ; A61K39/12 ; A61K39/145 ; A61K39/193 ; A61K39/21 ; A61K39/245 ; A61K39/275 ; A61K39/29 ; A61K39/395 ; A61K45/00 ; A61K48/00 ; A61P31/00 ; A61P31/04 ; A61P31/12 ; A61P35/00 ; A61P35/02 ; A61P37/04 ; C07K14/705 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N7/00 ; C12N7/01 ; C12P21/08 ; C12N15/00
摘要:
The present invention is a composition of recombinant virus which has incorporated into its genome or portion thereof a gene encoding an antigen to a disease causing agent and a recombinant virus which has incorporated into its genome or portion thereof a gene encoding an immunostimulatory molecule(s) for the purpose of stimulating an immune response against the disease causing agent. Methods of treatment of diseases such as cancer and diseases caused by pathogenic microorganisms is provide using the composition.
公开/授权文献
- US5020565A Water hammer absorber 公开/授权日:1991-06-04
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