发明授权
- 专利标题: Piperidine derivatives having renin inhibiting activity
- 专利标题(中): 具有肾素抑制活性的哌啶衍生物
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申请号: US255185申请日: 1999-02-22
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公开(公告)号: US6051712A公开(公告)日: 2000-04-18
- 发明人: Alfred Binggeli , Volker Breu , Daniel Bur , Walter Fischli , Rolf Guller , Georges Hirth , Hans-Peter Marki , Marcel Muller , Christian Oefner , Heinz Stadler , Eric Vieira , Maurice Wilhelm , Wolfgang Wostl
- 申请人: Alfred Binggeli , Volker Breu , Daniel Bur , Walter Fischli , Rolf Guller , Georges Hirth , Hans-Peter Marki , Marcel Muller , Christian Oefner , Heinz Stadler , Eric Vieira , Maurice Wilhelm , Wolfgang Wostl
- 申请人地址: NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: NJ Nutley
- 优先权: CHX2548/95 19950907; CHX1876/96 19960726
- 主分类号: C07D211/18
- IPC分类号: C07D211/18 ; A61K31/439 ; A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/445 ; A61K31/451 ; A61K31/4523 ; A61K31/47 ; A61K31/495 ; A61K31/505 ; A61K31/535 ; A61P9/00 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P13/02 ; A61P15/00 ; A61P27/02 ; C07D211/20 ; C07D211/22 ; C07D211/26 ; C07D211/32 ; C07D211/42 ; C07D211/44 ; C07D211/54 ; C07D211/56 ; C07D211/74 ; C07D401/02 ; C07D401/04 ; C07D401/06 ; C07D401/10 ; C07D401/12 ; C07D401/14 ; C07D405/04 ; C07D405/06 ; C07D405/12 ; C07D405/14 ; C07D409/10 ; C07D409/12 ; C07D413/10 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D471/08 ; C07D521/00
摘要:
Novel piperidine derivatives, their manufacture and use as medicaments, are disclosed. The invention is concerned with the novel piperidine derivatives of general formula I ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, Q, X, Z, m and n are as described herein.