发明授权
- 专利标题： 22025, a novel human cyclic nucleotide phosphodiesterase
- 专利标题（中）： 22025，一种新的人类环状核苷酸磷酸二酯酶
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申请号： US330970申请日： 1999-06-11
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公开(公告)号： US6146876A公开(公告)日： 2000-11-14
- 发明人: Keith E. Robision , Rosana Kapeller-Libermann , David White
- 申请人： Keith E. Robision , Rosana Kapeller-Libermann , David White
- 申请人地址： MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： MA Cambridge
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K38/00 ; A61P7/02 ; A61P9/10 ; A61P9/12 ; A61P11/06 ; A61P13/12 ; A61P15/08 ; A61P19/00 ; A61P19/10 ; A61P25/24 ; A61P25/28 ; A61P29/00 ; A61P37/06 ; A61P37/08 ; A61P43/00 ; C07K16/40 ; C12N5/10 ; C12N9/16 ; C12N15/09 ; C12N15/55 ; C12Q1/02 ; C12Q1/44 ; C12Q1/68 ; G01N33/566 ; C12N1/20 ; C07H21/04 ; C12N15/00
摘要：
The present invention relates to a newly identified human cyclic nucleotide phosphodiesterase belonging to the superfamily of mammalian phosphodiesterases. The invention also relates to polynucleotides encoding the phosphodiesterase. The invention further relates to methods using the phosphodiesterase polypeptides and polynucleotides as a target for diagnosis and treatment in phosphodiesterase-mediated or -related disorders. The invention further relates to drug-screening methods using the phosphodiesterase polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the phosphodiesterase polypeptides and polynucleotides. The invention further relates to procedures for producing the phosphodiesterase polypeptides and polynucleotides.
公开/授权文献
- US5472105A Hot-fillable plastic container with end grip 公开/授权日：1995-12-05