发明授权
- 专利标题： Development of method for screening physiologically active pyrrole imidazole derivative
- 专利标题（中）： 开发用于筛选生理活性吡咯咪唑衍生物的方法
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申请号： US09889379申请日： 2000-11-13
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公开(公告)号： US06974668B1公开(公告)日： 2005-12-13
- 发明人: Hiroshi Sugiyama , Isao Saito , Hirokazu Iida
- 申请人： Hiroshi Sugiyama , Isao Saito , Hirokazu Iida
- 申请人地址： JP Saitama
- 专利权人： Japan Science and Technology Corporation
- 当前专利权人： Japan Science and Technology Corporation
- 当前专利权人地址： JP Saitama
- 代理机构： Edwards & Angell, LLP
- 代理商 Peter F. Corless; John B. Alexander
- 优先权： JP11/326007 19991116
- 国际申请： PCT/JP00/07992 WO 20001113
- 国际公布： WO01/36677 WO 20010525
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; A61K31/4178 ; A61K31/70 ; A61K39/395 ; A61K49/00 ; A61P35/00 ; C07D487/04 ; C07H21/04 ; C12M1/26 ; C12Q1/02 ; C12Q1/04 ; C12Q1/68 ; G01N33/15 ; G01N33/50 ; G01N33/53 ; G01N33/566
摘要：
A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.
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