公开(公告)号：US06974668B1

公开(公告)日：2005-12-13

申请号：US09889379

申请日：2000-11-13

申请人： Hiroshi Sugiyama ,  Isao Saito ,  Hirokazu Iida

发明人： Hiroshi Sugiyama ,  Isao Saito ,  Hirokazu Iida

IPC分类号： C12N15/09 ,  A61K31/4178 ,  A61K31/70 ,  A61K39/395 ,  A61K49/00 ,  A61P35/00 ,  C07D487/04 ,  C07H21/04 ,  C12M1/26 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/50 ,  G01N33/53 ,  G01N33/566

CPC分类号： G01N33/5011

摘要： A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.

摘要翻译： 通过使用人造化学物质筛选片段A（化学物质A）对含有DNA或RNA的物质（例如细胞）的影响的方法。 即，通过使用能够识别DNA碱基序列的由以下通式（I）表示的一种或多种化学物质来检测或鉴定含有DNA或RNA的物质上的化学物质A的功能的方法; 一套工具; 和其中使用的板：B-L-A（I）其中B表示含有能够识别DNA碱基序列的非天然碱基的化学结构; A表示与DNA相互作用的化学结构; L表示连接物，化学结构A和B可以连接在一起。

公开(公告)号：US07378237B2

公开(公告)日：2008-05-27

申请号：US10285030

申请日：2002-11-01

申请人： Hiroshi Sugiyama ,  Isao Saito ,  Hirokazu Iida

发明人： Hiroshi Sugiyama ,  Isao Saito ,  Hirokazu Iida

IPC分类号： C12Q1/68 ,  A61K49/00 ,  A61K31/70 ,  A61K39/395

CPC分类号： G01N33/5011

摘要： A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.

摘要翻译： 通过使用人造化学物质筛选片段A（化学物质A）对含有DNA或RNA的物质（例如细胞）的影响的方法。 即，通过使用能够识别DNA碱基序列的由以下通式（I）表示的一种或多种化学物质来检测或鉴定含有DNA或RNA的物质上的化学物质A的功能的方法; 一套工具; 和其中使用的板：B-L-A（I）其中B表示含有能够识别DNA碱基序列的非天然碱基的化学结构; A表示与DNA相互作用的化学结构; L表示连接物，化学结构A和B可以连接在一起。

公开(公告)号：US07067622B2

公开(公告)日：2006-06-27

申请号：US10481275

申请日：2002-02-27

申请人： Hiroshi Sugiyama ,  Hirokazu Iida ,  Isao Saito ,  Takashi Saito

发明人： Hiroshi Sugiyama ,  Hirokazu Iida ,  Isao Saito ,  Takashi Saito

IPC分类号： C07K1/02

CPC分类号： C07D403/14

摘要： It is intended to provide a method of producing a pyrrole-imidazole polyamide whereby a longer pyrrole-imidazole polyamide can be conveniently synthesized and a peptide (protein) can be easily transferred. According to this method, a pyrrole-imidazole polyamide having a carboxylate group which can be excised from a solid phase carrier at its end, makes it possible to directly transfer various functional groups and can exactly distinguish DNA sequences can be efficiently produced. A method of synthesizing a pyrrole-imidazole polyamide characterized by performing automatic synthesis by the solid phase Fmoc method with the used of a peptide synthesizer; a pyrrole-imidazole polyamide having a carboxyl group at its end obtained by this method; a pyrrole-imidazole polyamide having a DNA alkylation agent transferred into the carboxyl group at the end of the above-described pyrrole-imidazole polyamide; and a sequence-specific DNA alkylation method characterized by using the above compound.

摘要翻译： 本发明提供一种制备吡咯 - 咪唑聚酰胺的方法，其中可以方便地合成较长的吡咯 - 咪唑聚酰胺，并且可以容易地转移肽（蛋白质）。 根据该方法，可以在其末端从固相载体上切割出具有羧酸酯基的吡咯 - 咪唑聚酰胺，从而可以直接转移各种官能团，并且能够精确地区分DNA序列。 一种合成吡咯 - 咪唑聚酰胺的方法，其特征在于使用肽合成仪通过固相Fmoc法进行自动合成; 通过该方法得到的具有羧基的吡咯 - 咪唑聚酰胺; 具有在上述吡咯 - 咪唑聚酰胺末端转移到羧基中的DNA烷基化剂的吡咯 - 咪唑聚酰胺; 特征在于使用上述化合物的序列特异性DNA烷基化方法。

公开(公告)号：US06946455B2

公开(公告)日：2005-09-20

申请号：US10030678

申请日：2001-05-01

申请人： Hiroshi Sugiyama ,  Toshikazu Bando ,  Hirokazu Iida ,  Isao Saito

发明人： Hiroshi Sugiyama ,  Toshikazu Bando ,  Hirokazu Iida ,  Isao Saito

IPC分类号： C12N15/00 ,  A61K31/407 ,  A61P35/00 ,  C07D487/04 ,  C07D487/10 ,  C07D519/00 ,  C12N15/01 ,  C12N15/09 ,  A61K31/33 ,  A01N43/38 ,  A01N43/90 ,  A61K31/44 ,  C07D209/56

CPC分类号： C07D487/04 ,  C07D487/10

摘要： Compounds represented by the general formula (I): which two DNA strands can be interstrand-crossliked: A-L-B-X-B-L-A  (I) wherein B represents a chemical structure capable of recognizing the nucleotide sequence of DNA; A represents a chemical structure capable of binding to one of the bases of DNA; L represents a linker by which the chemical structures of A and B can be linked to each other; X represents a spacer by which the A-L-B components can be linked to each other. A method of interstrand-crosslinking DNA by using these compounds; and medicinal compositions containing interstarand-crosslinking agents of DNA.

摘要翻译： 由通式（I）表示的化合物：两个DNA链可以是交联的：<？in-line-formula description =“In-line Formulas”end =“lead”？> ALBXBLA（I） line-formula description =“In-line Formulas”end =“tail”？>其中B表示能识别DNA核苷酸序列的化学结构; A表示能够结合DNA的一个碱基的化学结构; L表示A和B的化学结构可以彼此连接的连接体; X表示可以将A-L-B成分彼此连接的间隔物。 通过使用这些化合物进行链间交联DNA的方法; 以及含有星际交联剂的DNA的药物组合物。

公开(公告)号：US09081530B2

公开(公告)日：2015-07-14

申请号：US14168040

申请日：2014-01-30

申请人： Hirokazu Iida

发明人： Hirokazu Iida

IPC分类号： G06F3/12 ,  G06K15/00 ,  H04N1/60

CPC分类号： G06F3/1245 ,  G06F3/1203 ,  G06F3/1277

摘要： A control system for forming and outputting an image, in which an image output control apparatus cooperates with another information processing apparatus that instructs an image forming apparatus to form and output an image. The control system includes an intermediate data generator that acquires an image to be output and generates intermediate data as print data, an intermediate data storage processor that stores the generated intermediate data in a predetermined storage area, an intermediate data acquisition unit that acquires the intermediate data, an additional processor that executes an additional process in outputting the image based on the acquired intermediate data, and a print job generation controller that instructs a print job generator that generates a print job to instruct the image forming apparatus to execute forming and outputting the image to generate the print job based on the intermediate data.

摘要翻译： 一种用于形成和输出图像的控制系统，其中图像输出控制装置与指示图像形成装置形成和输出图像的另一信息处理装置协作。 控制系统包括中间数据生成器，其获取要输出的图像并生成作为打印数据的中间数据;中间数据存储处理器，其将所生成的中间数据存储在预定的存储区域;中间数据获取单元，其获取中间数据 执行基于获取的中间数据输出图像的附加处理的附加处理器，以及指示生成打印作业的打印作业生成器指示图像形成装置执行形成并输出图像的打印作业生成控制器 以基于中间数据生成打印作业。

公开(公告)号：US09311036B2

公开(公告)日：2016-04-12

申请号：US14287425

申请日：2014-05-27

申请人： Hirokazu Iida

发明人： Hirokazu Iida

IPC分类号： G06F3/12 ,  H04N1/21

CPC分类号： G06F3/1273 ,  G06F3/1203 ,  G06F3/1245 ,  G06F3/1259 ,  H04N1/21

摘要： A data processing system includes a first processor and a second processor and further includes an intermediate data generating unit that generates intermediate data; a first storage control unit that stores the intermediate data and identification data that identifies the intermediate data in correspondence with each other in a first storage area; a second storage control unit that stores the identification data in correspondence with the intermediate data in a second storage area; a process requesting unit that sends a request for processing the print data to an image processing apparatus; and an obtaining unit that obtains a processed result from the image processing apparatus based on the identification data.

摘要翻译： 数据处理系统包括第一处理器和第二处理器，并且还包括产生中间数据的中间数据生成单元; 第一存储控制单元，其在第一存储区域中存储中间数据和识别数据，所述中间数据和识别数据彼此对应地标识中间数据; 第二存储控制单元，其将与所述中间数据对应的所述识别数据存储在第二存储区域中; 处理请求单元，向所述图像处理装置发送处理所述打印数据的请求; 以及获取单元，其基于所述识别数据从所述图像处理设备获得处理结果。

公开(公告)号：US5963524A

公开(公告)日：1999-10-05

申请号：US859708

申请日：1997-05-21

申请人： Kazunori Tokiwa ,  Kenichi Horikiri ,  Hirokazu Iida

发明人： Kazunori Tokiwa ,  Kenichi Horikiri ,  Hirokazu Iida

IPC分类号： G11B7/00 ,  G11B7/004 ,  G11B7/09 ,  G11B7/125 ,  G11B7/135 ,  G11B19/12

CPC分类号： G11B19/12 ,  G11B7/0945 ,  G11B7/1365 ,  G11B7/139 ,  G11B2007/0006 ,  G11B7/0908 ,  G11B7/0925

摘要： An optical disk apparatus capable of automatically setting a pickup lens suitable for an optional optical disk selected from a plurality of optical disks having different thicknesses. Current flowing through an actuator is detected with a detector circuit, A/D converted, and supplied to a controller. The controller detects the in-focus positions at the surface and reflection film of an optical disk in accordance with an FOK signal and an FZC signal, calculates the current values flowing through the actuator at the in-focus positions, and judges the thickness of the optical disk in accordance with a difference between the current values.

摘要翻译： 一种光盘装置，其能够自动设置适于从具有不同厚度的多个光盘中选择的可选光盘的拾取镜头。 流过致动器的电流用检测器电路进行检测，A / D转换，并提供给控制器。 控制器根据FOK信号和FZC信号检测光盘的表面和反射膜上的对焦位置，计算在对焦位置处流过致动器的电流值，并且判断 光盘根据当前值之间的差异。

公开(公告)号：US10705777B2

公开(公告)日：2020-07-07

申请号：US16289769

申请日：2019-03-01

申请人： Hirokazu Iida

发明人： Hirokazu Iida

IPC分类号： G06F3/12 ,  H04N1/32 ,  H04N1/44

摘要： An information processing apparatus communicating with an image forming apparatus includes a memory that stores a program and a processor that executes the program stored in the memory to perform a process. The process includes receiving a first document file including multiple sets of encrypted page data of pages, arranging the sets of the encrypted page data in page order, attaching identification information for identifying a page data boundary to each of the arranged sets of the encrypted page data, obtaining decoding information for decoding the sets of the encrypted page data from the first document file, generating a second document file including the arranged sets of the encrypted page data and the decoding information disposed before the arranged sets of the encrypted page data, and transmitting the generated second document file to the image forming apparatus.

公开(公告)号：US5963730A

公开(公告)日：1999-10-05

申请号：US717670

申请日：1996-09-23

申请人： Masahiko Toyonaga ,  Michiaki Muraoka ,  Hirokazu Iida

发明人： Masahiko Toyonaga ,  Michiaki Muraoka ,  Hirokazu Iida

IPC分类号： G06F17/50

CPC分类号： G06F17/5045 ,  G06F17/5072

摘要： A netlist between functional macros is entered. Based on the netlist, an outline layout process for a functional macro is performed and physical specifications for the functional macro are determined from an outline layout produced by the outline layout process. Thereafter, a logic synthesis process is performed on the basis of the physical specifications determined. Based on the outline layout, a logic, obtained by the logic synthesis, is laid out. This makes it possible to reduce the number of times a circuit synthesis process is redone, taking into account a laying-out at an upper-stage functional design process in which no gate level is specified. For this reason, an improved LSI automatic design method is provided which is able to complete an LSI layout design, in which the LSI area and the LSI delay value are optimized, in a short period of time.

摘要翻译： 输入功能宏之间的网表。 基于网表，执行用于功能宏的轮廓布局处理，并且根据由轮廓布局处理产生的轮廓布局来确定功能宏的物理规格。 此后，基于所确定的物理规格执行逻辑合成处理。 基于大纲布局，通过逻辑综合得到逻辑。 这使得可以减少电路合成过程被重做的次数，同时考虑到在没有指定门级的上级功能设计过程中的布局。 因此，提供了一种改进的LSI自动设计方法，其能够在短时间内完成LSI面积和LSI延迟值被优化的LSI布局设计。

公开(公告)号：US11379174B2

公开(公告)日：2022-07-05

申请号：US16912891

申请日：2020-06-26

申请人： Masaki Arai ,  Hirokazu Iida

发明人： Masaki Arai ,  Hirokazu Iida

IPC分类号： G06F3/14 ,  H04L65/401 ,  H04L65/4038

摘要： According to one or more embodiments, an information processing system includes a plurality of communication terminals, each installed with a web browser; and an information processing apparatus. The information processing apparatus includes first circuitry configured to: determine occurrence of a trigger to capture an image of a shared screen to be shared by the plurality of communication terminals; generate data of a web page including the image of the shared screen captured based on the occurrence of the trigger; and transmit the data of the web page to the plurality of communication terminals. Each of the plurality of communication terminals includes second circuitry configured to display the web page including the image of the shared screen based on the data received from the information processing apparatus.