Invention Grant
- Patent Title: Producing optically active amino compounds
- Patent Title (中): 生产光学活性氨基化合物
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Application No.: US10112706Application Date: 2002-04-02
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Publication No.: US07169592B2Publication Date: 2007-01-30
- Inventor: Yukio Yamada , Akira Iwasaki , Noriyuki Kizaki , Keiji Matsumoto , Yasuhiro Ikenaka , Masahiro Ogura , Junzo Hasegawa
- Applicant: Yukio Yamada , Akira Iwasaki , Noriyuki Kizaki , Keiji Matsumoto , Yasuhiro Ikenaka , Masahiro Ogura , Junzo Hasegawa
- Applicant Address: JP Osaka
- Assignee: Kaneka Corporation
- Current Assignee: Kaneka Corporation
- Current Assignee Address: JP Osaka
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP9-121732 19970423
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12N1/21 ; C12N15/54 ; C12N15/63 ; C12N15/82 ; C12N15/85 ; C07H21/04
Abstract:
To provide a method for preparing optically active compounds, which mainly contain (R)-amino compounds, by microbial enzymes efficiently and inexpensively; a polypeptide having stereoselective transaminase activity which can be suitably used for the above preparation method; and a DNA encoding the polypeptide. A method for preparing an optically active amino compound, characterized in stereoselectively transaminating by acting a transaminase on an amino group acceptor, a ketone compound in the presence of an amino group donor, a primary amine; a DNA comprising a nucleotide sequence encoding a polypeptide having stereoselective transaminase activity; and a polypeptide having stereoselective transaminase activity obtainable from a culture of a microorganism belonging to the genus Arthrobacter.
Public/Granted literature
- US20020192786A1 Producing optically active amino compounds Public/Granted day:2002-12-19
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