发明授权
- 专利标题： Thio-substituted biaryl-methanesulfinyl derivatives
- 专利标题（中）： 硫取代的联芳基 - 甲亚磺酰基衍生物
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申请号： US11104091申请日： 2005-04-12
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公开(公告)号： US07449481B2公开(公告)日： 2008-11-11
- 发明人: Edward R. Bacon , Sankar Chatterjee , Derek Dunn , Marie-Edith Gourdel , Greg Hostetler , Mohamed Iqbal , Brigitte Lesur , Philippe Louvet , Eric Riguet , Dominique Schweizer , Christophe Yue
- 申请人： Edward R. Bacon , Sankar Chatterjee , Derek Dunn , Marie-Edith Gourdel , Greg Hostetler , Mohamed Iqbal , Brigitte Lesur , Philippe Louvet , Eric Riguet , Dominique Schweizer , Christophe Yue
- 申请人地址： US PA Frazer
- 专利权人： Cephalon, Inc.
- 当前专利权人： Cephalon, Inc.
- 当前专利权人地址： US PA Frazer
- 优先权： EP04290982 20040413
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; C07D333/02
摘要：
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted biaryl-methanesulfinyl acetamides of Formula (I): wherein Ar, Y, R1, R2, R4, R5, q and x are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness associated with narcolepsy, obstructive sleep apnea, or shift work disorder; Parkinson's disease; Alzheimer's disease; attention deficit disorder; attention deficit hyperactivity disorder; depression; or fatigue associated with a neurological disease; as well as the promotion of wakefulness.
公开/授权文献
- US20050245747A1 Thio-substituted biaryl-methanesulfinyl derivatives 公开/授权日：2005-11-03
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