- 专利标题: Pharmaceutical use of alpha antigen or alpha antigen gene
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申请号: US11352342申请日: 2006-02-13
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公开(公告)号: US07524675B2公开(公告)日: 2009-04-28
- 发明人: Yasuhiro Yasutomi , Hitoshi Mizutani
- 申请人: Yasuhiro Yasutomi , Hitoshi Mizutani
- 申请人地址: JP Osaka
- 专利权人: Maruho Co., Ltd.
- 当前专利权人: Maruho Co., Ltd.
- 当前专利权人地址: JP Osaka
- 代理机构: Sughrue Mion, PLLC
- 优先权: JP2001-043291 20010220
- 主分类号: C12N15/00
- IPC分类号: C12N15/00 ; A61K31/711 ; C07H21/04
摘要:
The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of allergic diseases such as IgE production, histamine release and eosinophil infiltration, and therefore they are very effective for the prevention or treatment of atopic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis, and more broadly allergic diseases.