Pharmaceutical Use of Alpha Antigen or Alpha Antigen Gene
    2.
    发明申请
    Pharmaceutical Use of Alpha Antigen or Alpha Antigen Gene 审中-公开
    α抗原或α抗原基因的药物用途

    公开(公告)号:US20090286734A1

    公开(公告)日:2009-11-19

    申请号:US12405844

    申请日:2009-03-17

    IPC分类号: A61K38/16 A61P17/00

    CPC分类号: A61K39/04 A61K2039/53

    摘要: The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of allergic diseases such as IgE production, histamine release and eosinophil infiltration, and therefore they are very effective for the prevention or treatment of atopic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis, and more broadly allergic diseases.

    摘要翻译: α抗原编码基因和α抗原蛋白抑制白细胞介素-4等的产生,改善Th2型细胞因子显性状态,进一步抑制IgE产生,组胺释放和嗜酸性粒细胞浸润等过敏性疾病的各种病症, 因此它们对预防或治疗特应性皮炎,哮喘,过敏性鼻炎和过敏性结膜炎等特应性疾病以及更广泛的过敏性疾病非常有效。

    Pharmaceutical use of α antigen or α antigen gene
    4.
    发明授权
    Pharmaceutical use of α antigen or α antigen gene 有权
    药物使用α抗原或α抗原基因

    公开(公告)号:US07622297B2

    公开(公告)日:2009-11-24

    申请号:US11896977

    申请日:2007-09-07

    CPC分类号: A61K39/04 A61K2039/53

    摘要: The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of allergic diseases such as IgE production, histamine release and eosinophil infiltration, and therefore they are very effective for the prevention or treatment of atopic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis, and more broadly allergic diseases.

    摘要翻译: α抗原编码基因和α抗原蛋白抑制白细胞介素-4等的产生,改善Th2型细胞因子显性状态,进一步抑制IgE产生,组胺释放和嗜酸性粒细胞浸润等过敏性疾病的各种病症, 因此它们对预防或治疗特应性皮炎,哮喘,过敏性鼻炎和过敏性结膜炎等特应性疾病以及更广泛的过敏性疾病非常有效。

    Pharmaceutical use of alpha antigen or alpha antigen gene
    5.
    发明申请
    Pharmaceutical use of alpha antigen or alpha antigen gene 有权
    药物使用α抗原或α抗原基因

    公开(公告)号:US20080132463A1

    公开(公告)日:2008-06-05

    申请号:US11896977

    申请日:2007-09-07

    IPC分类号: A61K31/70 A61P43/00

    CPC分类号: A61K39/04 A61K2039/53

    摘要: The α antigen-encoding gone and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of allergic diseases such as IgE production, histamine release and eosinophil infiltration, and therefore they are very effective for the prevention or treatment of atopic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis, and more broadly allergic diseases.

    摘要翻译: α抗原编码去除和α抗原蛋白抑制白细胞介素-4等的产生,改善Th2型细胞因子主导状态,进而抑制IgE产生,组胺释放和嗜酸性粒细胞浸润等过敏性疾病的各种病症, 因此它们对预防或治疗特应性皮炎,哮喘,过敏性鼻炎和过敏性结膜炎等特应性疾病以及更广泛的过敏性疾病非常有效。

    Data processing method and data analysis apparatus
    6.
    发明授权
    Data processing method and data analysis apparatus 有权
    数据处理方法和数据分析装置

    公开(公告)号:US08219548B2

    公开(公告)日:2012-07-10

    申请号:US11851457

    申请日:2007-09-07

    IPC分类号: G06F17/30 G06F11/34

    CPC分类号: G06Q10/06 G06F11/3476

    摘要: The execution of a process is analyzed by a data processing method using a data analysis device for processing a job by combining the processes of transforming input data and generating output data. The execution history of the process is recorded, and each time the process is executed, it is determined whether the process execution has a high anomaly probability based on a predetermined determination indicator. Upon determining that the process execution has a high anomaly probability, the process log information of the process including the determination indicator is recorded, and based on the process log information and the process execution history, the process with the high anomaly probability is further analyzed. By determining whether the process is anomalous or not, the process history analysis information including the analysis result and the execution history of the process to be analyzed is generated.

    摘要翻译: 通过使用数据分析装置通过组合变换输入数据和生成输出数据的处理来处理作业的数据处理方法来分析处理的执行。 记录处理的执行历史,并且每当执行处理时,基于预定的确定指示符确定处理执行是否具有高的异常概率。 在确定过程执行具有高异常概率时,记录包括确定指示符的处理的处理日志信息,并且基于处理日志信息和处理执行历史,进一步分析具有高异常概率的处理。 通过确定该过程是否是异常的,生成包括分析结果和待分析过程的执行历史的处理历史分析信息。

    Spread illuminating apparatus to illuminate two liquid crystal display panels different in screen size
    7.
    发明授权
    Spread illuminating apparatus to illuminate two liquid crystal display panels different in screen size 有权
    展开照明装置照亮两个不同屏幕尺寸的液晶显示面板

    公开(公告)号:US07248308B2

    公开(公告)日:2007-07-24

    申请号:US10726682

    申请日:2003-12-04

    IPC分类号: G02F1/1335

    摘要: A spread illuminating apparatus includes: at least one light source; a light conductive plate which has the at least one light source disposed at one end surface thereof, and which allows light emitted from the at least one light source and introduced therein to exit out therefrom through both major surfaces thereof toward first and second liquid crystal display elements disposed respectively over the both major surfaces of the light conductive plate, wherein the second liquid crystal display element has a smaller display screen size than the first liquid crystal display element; and a reflecting means which is disposed at the other major surface of the light conductive plate so as to cover at least areas not covered by the second liquid crystal display element, and which reflects light toward the first liquid crystal display element.

    摘要翻译: 扩展照明装置包括:至少一个光源; 导光板,其至少一个光源设置在其一个端面,并且允许从所述至少一个光源发射并从其中引入的光通过其两个主表面从第一和第二液晶显示器 分别设置在导光板的两个主表面上的元件,其中第二液晶显示元件具有比第一液晶显示元件更小的显示屏尺寸; 以及反射装置,其设置在导光板的另一个主表面上,以便至少覆盖未被第二液晶显示元件覆盖的区域,并将光朝第一液晶显示元件反射。

    Caspase 1 gene transfer animal
    8.
    发明授权
    Caspase 1 gene transfer animal 有权
    半胱天冬酶1基因转移动物

    公开(公告)号:US07067712B2

    公开(公告)日:2006-06-27

    申请号:US10311211

    申请日:2001-06-15

    申请人: Hitoshi Mizutani

    发明人: Hitoshi Mizutani

    摘要: A transgenic rodent or its offspring which carries DNA having an exogenous caspase 1 gene integrated thereinto in such a manner as to express the gene specifically to the skin. The transgenic rodent of the present invention spontaneously develops atopic dermatitis in the absence of any specific pathogenic microorganism and is useful as a disease model animal. The transgenic rodent of the present invention is useful for developing preventive and/or therapeutic drugs for atopic dermatitis based on natural immunity and to clarify the onset mechanism of atopic diseases.

    摘要翻译: 转基因啮齿动物或其后代,其携带具有整合到其中的外源半胱天冬酶1基因的DNA,以便将该基因特异性表达于皮肤。 本发明的转基因啮齿类动物在没有任何特异性致病微生物的情况下自发发生特应性皮炎,并且可用作疾病模型动物。 本发明的转基因啮齿类动物可用于开发基于天然免疫的特应性皮炎的预防和/或治疗药物,并阐明特应性疾病的发病机制。

    Spread illuminating apparatus with light conductive plate having polygonal configuration
    9.
    发明授权
    Spread illuminating apparatus with light conductive plate having polygonal configuration 失效
    具有多边形结构的导光板的散光照明装置

    公开(公告)号:US07056004B2

    公开(公告)日:2006-06-06

    申请号:US10777035

    申请日:2004-02-13

    IPC分类号: F21V7/04

    摘要: In a spread illuminating apparatus comprising a spot-like light source, and a light conductive plate, the light conductive plate is shaped into a pentagon which has two sides thereof substantially parallel to each other. The pentagon includes, as a part thereof, a triangle having its base defined by an imaginary line connecting respective straightly opposing ends of the two parallel sides, and the spot-like light source is disposed at a side of the pentagon constituting one of two hypotenuses of the triangle.

    摘要翻译: 在包括斑点状光源和导光板的扩散照明装置中,将导光板成形为具有彼此大致平行的两侧的五边形。 五角形作为其一部分包括三角形,其三角形具有由连接两个平行边的相应直的相对端的虚拟线限定的基部,并且点状光源设置在构成两个斜边之一的五边形的一侧 的三角形。

    Rotary pump for braking device
    10.
    发明申请
    Rotary pump for braking device 有权
    制动装置用旋转泵

    公开(公告)号:US20060093507A1

    公开(公告)日:2006-05-04

    申请号:US11259059

    申请日:2005-10-27

    摘要: The curvature of a circular arc constituted by a side of a suction groove is made larger than that of a circular arc constituted by a side of a discharge groove. Thus, when the suction groove and the discharge groove are viewed in the axial direction of a drive shaft, the distance between the suction groove and the discharge groove in the radial direction of a rotary portion is short in a region intersecting with a line W perpendicular to a centerline, and increases in accordance with a decrease in distance from containment portions. It is therefore possible to ensure a sufficient distance between the discharge and suction grooves and enhance a total fluid pressure generated therebetween, and the contact surface pressure that is necessitated by a second side plate to obtain a press-back force when being in contact with an outer rotor and an inner rotor is reduced.

    摘要翻译: 由吸引槽的一侧构成的圆弧的曲率比由排出槽的一侧构成的圆弧的曲率大。 因此,当在驱动轴的轴向上观察吸入槽和排出槽时,旋转部的径向方向上的吸入槽和排出槽之间的距离在垂直于线W的区域中短 到中心线,并且随着距离容纳部分的距离的减小而增加。 因此,可以确保排出和吸入槽之间的足够的距离,并增强其间产生的总的流体压力,以及当与第二侧板接触时获得压靠力所需的接触表面压力 外转子和内转子减少。