METHOD AND APPARATUS FOR LOADING SUTURE
    1.
    发明公开

    公开(公告)号:US20240358367A1

    公开(公告)日:2024-10-31

    申请号:US18767797

    申请日:2024-07-09

    申请人: Maruho Co., Ltd.

    IPC分类号: A61B17/06

    摘要: A loader is disclosed that can load a suture and/or a shuttle into a suture device. The loader can have a suture and/or a shuttle that can be moved (e.g., via a loader control) from a non-loaded configuration to a loaded configuration without damaging the suture or the shuttle. The shuttle can be moved from a shuttle first position to a shuttle second position. When the shuttle is in the shuttle first position, a suture device can be positionable in a device space on the loader. When the suture device is positioned in the device space, the shuttle can be moved from the shuttle first position to the shuttle second position. When the shuttle is in the shuttle first position, the shuttle can be outside the suture device. When the shuttle is in the shuttle second position, the shuttle can be inside the suture device.

    SKIN COMPOSITION
    2.
    发明申请

    公开(公告)号:US20220105237A1

    公开(公告)日:2022-04-07

    申请号:US17427902

    申请日:2020-02-03

    申请人: Maruho Co., Ltd.

    IPC分类号: A61L26/00

    摘要: It is an object of the present invention to provide a film-forming composition for skin (such as a film-type skin protectant or a film-type skin topical agent) that does not contain a lower monohydric alcohol such as ethanol or isopropanol, is excellent in quick-drying properties and water resistance, is less sticky, and is excellent in feeling of use. The present invention relates to a film-forming composition for skin which contains a specific acrylic polymer, a plasticizer and water and is substantially free of a lower monohydric alcohol such as ethanol or isopropanol. The composition of the present invention is extremely useful for treatment of chronic skin diseases (that is, skin diseases in which skin barrier function is deteriorated) represented by hand eczema, atopic dermatitis, and the like.

    Remedy for pemphigoid
    4.
    发明申请
    Remedy for pemphigoid 失效
    补救天疱疮

    公开(公告)号:US20060104947A1

    公开(公告)日:2006-05-18

    申请号:US10518759

    申请日:2003-12-26

    申请人: Takekuni Nakama

    发明人: Takekuni Nakama

    IPC分类号: A61K38/21 A61K31/573

    CPC分类号: A61K38/217

    摘要: An agent for treatment of pemphigoid is provided. For use as an agent for treatment of pemphigoid, IFN-γ is administered in a dose of 2,000,000 JRU once daily for 7 days by intravenous drip infusion. Depending on symptoms, side effects and age of a patient, the dose can be change, or the dosage can changed to intravenous drip infusion given once in several days. IFN-γ is fast-acting against pemphigoid, involves few side effects, and is considered to be effective. The mechanism of action is presumed to be that IFN-γ suppresses the chemotaxis and function of eosinophils which are considered to be directly involved in the occurrence of pemphigoid.

    摘要翻译: 提供了治疗类天疱疮的药剂。 为了用作治疗类天疱疮的药剂,通过静脉滴注,IFN-γ每天一次以2,000,000 JRU的剂量给药7天。 根据患者的症状,副作用和年龄,剂量可以改变,或剂量可以改变为在几天内给予一次静脉滴注。 IFN-γ是快速作用于类天疱疮,涉及很少的副作用,被认为是有效的。 推定作用机制是IFN-γ抑制被认为直接参与类天疱疮发生的嗜酸性粒细胞的趋化性和功能。

    Medical skin external preparation

    公开(公告)号:US11439634B2

    公开(公告)日:2022-09-13

    申请号:US16465559

    申请日:2017-11-30

    申请人: Maruho Co., Ltd.

    摘要: An object of the present invention is mainly to provide a medical skin external preparation that is suitable for treating superficial skin infections, in particular, superficial skin infections accompanied by blister or erosion, etc. For example, the present invention can provide a medical skin external preparation containing 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof as an active ingredient, and an alcohol and/or a fatty acid having 12 or more carbon atoms.

    DEFORMED NAIL CORRECTOR
    6.
    发明申请
    DEFORMED NAIL CORRECTOR 有权
    变形指甲修正器

    公开(公告)号:US20150230967A1

    公开(公告)日:2015-08-20

    申请号:US14425198

    申请日:2013-08-30

    IPC分类号: A61F5/11

    CPC分类号: A61F5/11

    摘要: A deformed nail corrector for correcting a deformed nail is provided that includes: a first elastic wire which has one end portion thereof fixed to one edge of the deformed nail in a width direction; a second elastic wire which has one end portion thereof fixed to the other edge of the deformed nail in the width direction; and a binding means which binds the first and second elastic wires to each other and is slidable along the first and second elastic wires in a bound state. The first and second elastic wires are brought into a state where the first and second wires are deformed along the deformed nail with the first and second, elastic wires being in a corrector mounting state where the first and second elastic wires are bound to each other by the binding means.

    摘要翻译: 提供了一种用于矫正变形钉的变形指甲矫正器,包括:第一弹性线,其一端部沿宽度方向固定在变形钉的一个边缘上; 第二弹性线,其一端部沿宽度方向固定在变形钉的另一边缘上; 以及捆绑装置,其将第一和第二弹性线彼此结合并且可以沿着第一和第二弹性线在绑定状态下滑动。 第一弹性线和第二弹性线处于第一和第二线沿着变形的钉变形的状态,第一和第二弹性线处于校正器安装状态,其中第一和第二弹性线彼此结合, 绑定手段。

    Pharmaceutical Use of Alpha Antigen or Alpha Antigen Gene
    7.
    发明申请
    Pharmaceutical Use of Alpha Antigen or Alpha Antigen Gene 审中-公开
    α抗原或α抗原基因的药物用途

    公开(公告)号:US20090286734A1

    公开(公告)日:2009-11-19

    申请号:US12405844

    申请日:2009-03-17

    IPC分类号: A61K38/16 A61P17/00

    CPC分类号: A61K39/04 A61K2039/53

    摘要: The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of allergic diseases such as IgE production, histamine release and eosinophil infiltration, and therefore they are very effective for the prevention or treatment of atopic diseases such as atopic dermatitis, asthma, allergic rhinitis, and allergic conjunctivitis, and more broadly allergic diseases.

    摘要翻译: α抗原编码基因和α抗原蛋白抑制白细胞介素-4等的产生,改善Th2型细胞因子显性状态,进一步抑制IgE产生,组胺释放和嗜酸性粒细胞浸润等过敏性疾病的各种病症, 因此它们对预防或治疗特应性皮炎,哮喘,过敏性鼻炎和过敏性结膜炎等特应性疾病以及更广泛的过敏性疾病非常有效。