发明授权
US08338132B2 Nucleic acids encoding receptor for IL-17 homologous polypeptides and therapeutic uses thereof
有权
编码IL-17同源多肽的受体的核酸及其治疗用途
- 专利标题： Nucleic acids encoding receptor for IL-17 homologous polypeptides and therapeutic uses thereof
- 专利标题（中）： 编码IL-17同源多肽的受体的核酸及其治疗用途
-
申请号： US12412796申请日： 2009-03-27
-
公开(公告)号： US08338132B2公开(公告)日： 2012-12-25
- 发明人: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , J. Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Sarah G. Hymowitz , Daniel Tumas , Melissa A. Starovasnik , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
- 申请人： Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , J. Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Sarah G. Hymowitz , Daniel Tumas , Melissa A. Starovasnik , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
- 申请人地址： US CA South San Francisco
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Arnold & Porter LLP
- 代理商 Bonny Yeung; Barrie D. Bell
- 主分类号： C12N15/09
- IPC分类号： C12N15/09
摘要：
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
公开/授权文献
信息查询
IPC分类:
