Invention Grant
US08338132B2 Nucleic acids encoding receptor for IL-17 homologous polypeptides and therapeutic uses thereof
有权
编码IL-17同源多肽的受体的核酸及其治疗用途
- Patent Title: Nucleic acids encoding receptor for IL-17 homologous polypeptides and therapeutic uses thereof
- Patent Title (中): 编码IL-17同源多肽的受体的核酸及其治疗用途
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Application No.: US12412796Application Date: 2009-03-27
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Publication No.: US08338132B2Publication Date: 2012-12-25
- Inventor: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , J. Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Sarah G. Hymowitz , Daniel Tumas , Melissa A. Starovasnik , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
- Applicant: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , J. Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Sarah G. Hymowitz , Daniel Tumas , Melissa A. Starovasnik , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Arnold & Porter LLP
- Agent Bonny Yeung; Barrie D. Bell
- Main IPC: C12N15/09
- IPC: C12N15/09
Abstract:
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Public/Granted literature
- US20090227016A1 IL-17 HOMOLOGOUS POLYPEPTIDES AND THERAPEUTIC USES THEREOF Public/Granted day:2009-09-10
Information query
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