Invention Grant
- Patent Title: 7-substituted tetracycline compounds
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Application No.: US12481368Application Date: 2009-06-09
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Publication No.: US08492365B2Publication Date: 2013-07-23
- Inventor: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
- Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
- Applicant Address: US MA Boston US MA Boston
- Assignee: Trustees of Tufts College,Paratek Pharmaceuticals, Inc.
- Current Assignee: Trustees of Tufts College,Paratek Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston US MA Boston
- Agency: McCarter & English, LLP
- Main IPC: A61K31/65
- IPC: A61K31/65 ; A61K31/42 ; A61K31/426 ; A61K31/4402 ; A61K31/505 ; A61K31/5375 ; C07C237/26 ; C07D239/26 ; C07D295/104 ; C07D261/08 ; C07D277/42

Abstract:
The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Public/Granted literature
- US20090306022A1 7-SUBSTITUTED TETRACYCLINE COMPOUNDS Public/Granted day:2009-12-10
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