-
公开(公告)号：US07595309B2
公开(公告)日：2009-09-29
申请号：US10853635
申请日：2004-05-24
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Beena Bhatia , David Messersmith , Mohamed Y. Ismail , Todd Bowser , Laura McIntyre , Darrell J. Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul K. Verma , Tadeusz Warchol , Upul Bandarage
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Beena Bhatia , David Messersmith , Mohamed Y. Ismail , Todd Bowser , Laura McIntyre , Darrell J. Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul K. Verma , Tadeusz Warchol , Upul Bandarage
IPC: A61K31/65 , C07C43/00 , C07D221/18
CPC classification number: C07D213/64 , C07C237/26 , C07C251/24 , C07C251/48 , C07C271/22 , C07C271/28 , C07C271/58 , C07C275/24 , C07C311/06 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2603/46 , C07D207/22 , C07D213/50 , C07D213/56 , C07D239/36 , C07D261/18 , C07D277/30 , C07D277/42 , C07D295/096 , C07D295/135 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/28 , C07D333/60 , C07F9/2475
Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Abstract translation: 本发明至少部分地涉及新的7-取代四环素化合物。 这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US20070072834A1
公开(公告)日：2007-03-29
申请号：US11397445
申请日：2006-04-04
Applicant: Mark Nelson , Beena Bhatia , Laura McIntyre , Glen Rennie
Inventor： Mark Nelson , Beena Bhatia , Laura McIntyre , Glen Rennie
IPC: A61K31/65 , C07C237/26
CPC classification number: C07C231/12 , C07C237/26
Abstract: 13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described.
Abstract translation: 描述了13-取代的甲基环霉素化合物，治疗四环素应答状态的方法和含有13-取代的甲基环霉素化合物的药物组合物。
-
公开(公告)号：US20050143353A1
公开(公告)日：2005-06-30
申请号：US11015966
申请日：2004-12-17
Applicant: Mark Nelson , Beena Bhatia , Laura McIntyre , Glen Rennie
Inventor： Mark Nelson , Beena Bhatia , Laura McIntyre , Glen Rennie
IPC: C07C237/26 , A61K31/65
CPC classification number: C07C231/12 , C07C237/26
Abstract: 13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described.
Abstract translation: 描述了13-取代的甲基环霉素化合物，治疗四环素应答状态的方法和含有13-取代的甲基环霉素化合物的药物组合物。
-
公开(公告)号：US20100160263A1
公开(公告)日：2010-06-24
申请号：US12617111
申请日：2009-11-12
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Laura McIntyre , Beena Bhatia , Paul Hawkins , Laxma Reddy Nagavelli , Karen Stepleton , Tad Warchol , Paul Sheahan
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Laura McIntyre , Beena Bhatia , Paul Hawkins , Laxma Reddy Nagavelli , Karen Stepleton , Tad Warchol , Paul Sheahan
IPC: A61K31/65 , C07C237/26 , C07D403/10 , C07D213/30 , C07D215/14 , A61P31/00
CPC classification number: C07C237/26 , B32B37/0007 , B32B37/003 , B32B37/1284 , C07C2601/14 , C07C2601/16 , C07C2603/46 , C07D209/48 , C07D213/82 , C07D215/14 , C07D307/24 , C07D317/60
Abstract: The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Abstract translation: 本发明涉及新的7,9-取代的四环素化合物。 这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US20060148765A1
公开(公告)日：2006-07-06
申请号：US11305048
申请日：2005-12-16
Applicant: Mark Nelson , Laura McIntyre
Inventor： Mark Nelson , Laura McIntyre
IPC: A61K31/65 , C07D323/02
CPC classification number: C07D323/02 , C07C237/26 , C07C2603/46 , C07D317/60
Abstract: 7-substituted fused ring tetracycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 7-substituted fused ring tetracycline compounds are described.
-
Patent Agency Ranking
公开(公告)号：US06683068B2
公开(公告)日：2004-01-27
申请号：US09895797
申请日：2001-06-29
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Laura McIntyre , Beena Bhatia , Paul Hawkins , Laxma Reddy , Karen Stapleton , Tad Warchol , Paul Sheahan
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Laura McIntyre , Beena Bhatia , Paul Hawkins , Laxma Reddy , Karen Stapleton , Tad Warchol , Paul Sheahan
IPC: A61K3165
CPC classification number: C07C237/26 , B32B37/0007 , B32B37/003 , B32B37/1284 , C07C2601/14 , C07C2601/16 , C07C2603/46 , C07D209/48 , C07D213/82 , C07D215/14 , C07D307/24 , C07D317/60
Abstract: The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Abstract translation: 本发明涉及新的7,9-取代的四环素化合物。 这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US08492365B2
公开(公告)日：2013-07-23
申请号：US12481368
申请日：2009-06-09
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
IPC: A61K31/65 , A61K31/42 , A61K31/426 , A61K31/4402 , A61K31/505 , A61K31/5375 , C07C237/26 , C07D239/26 , C07D295/104 , C07D261/08 , C07D277/42
CPC classification number: C07D213/64 , C07C237/26 , C07C251/24 , C07C251/48 , C07C271/22 , C07C271/28 , C07C271/58 , C07C275/24 , C07C311/06 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2603/46 , C07D207/22 , C07D213/50 , C07D213/56 , C07D239/36 , C07D261/18 , C07D277/30 , C07D277/42 , C07D295/096 , C07D295/135 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/28 , C07D333/60 , C07F9/2475
Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
-
公开(公告)号：US08048867B2
公开(公告)日：2011-11-01
申请号：US10839023
申请日：2004-05-04
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Y. Ismail , Todd Bowser , Jimmy Dumornay , Glen Rennie , Gui Liu , Darrell J. Koza , Paul Sheahan , Karen Stapleton , Paul Hawkins , Beena Bhatia , Atul K. Verma , Laura McIntyre , Tadeusz Warchol , David Messersmith
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Y. Ismail , Todd Bowser , Jimmy Dumornay , Glen Rennie , Gui Liu , Darrell J. Koza , Paul Sheahan , Karen Stapleton , Paul Hawkins , Beena Bhatia , Atul K. Verma , Laura McIntyre , Tadeusz Warchol , David Messersmith
IPC: A61K31/59 , C07C401/00
CPC classification number: A61K31/65 , C07C237/26 , C07C255/59 , C07C271/22 , C07C271/28 , C07C271/30 , C07C271/58 , C07C275/30 , C07C275/34 , C07C275/38 , C07C275/40 , C07C275/42 , C07C275/50 , C07C275/54 , C07C311/06 , C07C311/21 , C07C333/08 , C07C335/22 , C07C381/10 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2601/16 , C07C2603/46 , C07D295/155 , C07F9/4006 , C07F9/4056 , Y02A50/473 , Y02A50/481
Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Abstract translation: 本发明至少部分地涉及新的9-取代的米诺环素化合物。 这些米诺环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US07696186B2
公开(公告)日：2010-04-13
申请号：US10738862
申请日：2003-12-16
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Y. Ismail , Todd Bowser , Laura McIntyre , Beena Bhatia , Paul Hawkins , Laxma Reddy , Karen Stapleton , Tadeusz Warchol , Paul Sheahan
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Y. Ismail , Todd Bowser , Laura McIntyre , Beena Bhatia , Paul Hawkins , Laxma Reddy , Karen Stapleton , Tadeusz Warchol , Paul Sheahan
IPC: A61K31/65 , C07C237/28
CPC classification number: C07C237/26 , B32B37/0007 , B32B37/003 , B32B37/1284 , C07C2601/14 , C07C2601/16 , C07C2603/46 , C07D209/48 , C07D213/82 , C07D215/14 , C07D307/24 , C07D317/60
Abstract: The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Abstract translation: 本发明涉及新的7,9-取代的四环素化合物。 这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
公开(公告)号：US20090306022A1
公开(公告)日：2009-12-10
申请号：US12481368
申请日：2009-06-09
Applicant: Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
Inventor： Mark L. Nelson , Roger Frechette , Peter Viski , Mohamed Ismail , Todd Bowser , Beena Bhatia , David Messersmith , Laura McIntyre , Darrell Koza , Glen Rennie , Paul Sheahan , Paul Hawkins , Atul Verma , Tadeusz Warchol , Upul Bandarage
IPC: A61K31/65 , C07C237/26 , C07D277/38 , C07D333/24 , C07D213/56 , C07D307/54 , C07D239/52 , C07D413/06 , C07D239/34
CPC classification number: C07D213/64 , C07C237/26 , C07C251/24 , C07C251/48 , C07C271/22 , C07C271/28 , C07C271/58 , C07C275/24 , C07C311/06 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07C2603/46 , C07D207/22 , C07D213/50 , C07D213/56 , C07D239/36 , C07D261/18 , C07D277/30 , C07D277/42 , C07D295/096 , C07D295/135 , C07D295/155 , C07D307/54 , C07D307/68 , C07D307/79 , C07D317/60 , C07D333/24 , C07D333/28 , C07D333/60 , C07F9/2475
Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
Abstract translation: 本发明至少部分地涉及新的7-取代四环素化合物。 这些四环素化合物可用于治疗多种四环素化合物反应状态，例如细菌感染和肿瘤，以及其他已知的米诺环素和四环素化合物的一般应用，例如阻断四环素外排和调节基因表达。
-
-
-
-
-
-
-
-
-
Search Results
15
records
(took 0.015 seconds)
