- 专利标题： Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
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申请号： US12951344申请日： 2010-11-22
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公开(公告)号： US08580794B2公开(公告)日： 2013-11-12
- 发明人: George A. Doherty , Steven W. Elmore , Lisa A. Hasvold , Andrew J. Souers , Zhi-Fu Tao , Gary T. Wang , Le Wang , Robert Mantei , Todd M. Hansen
- 申请人： George A. Doherty , Steven W. Elmore , Lisa A. Hasvold , Andrew J. Souers , Zhi-Fu Tao , Gary T. Wang , Le Wang , Robert Mantei , Todd M. Hansen
- 申请人地址： US IL North Chicago
- 专利权人： AbbVie Inc.
- 当前专利权人： AbbVie Inc.
- 当前专利权人地址： US IL North Chicago
- 代理机构： Jones Day
- 主分类号： A61K31/407
- IPC分类号： A61K31/407 ; C07D401/12
摘要：
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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