发明授权
- 专利标题： Humanized anti-CD47 antibody
- 专利标题（中）： 人源化抗CD47抗体
-
申请号： US13329658申请日： 2011-12-19
-
公开(公告)号： US08759025B2公开(公告)日： 2014-06-24
- 发明人: Yasufumi Kikuchi , Shinsuke Uno , Yasuko Kinoshita , Shigeyuki Iijima , Naoshi Fukushima , Masayuki Tsuchiya
- 申请人： Yasufumi Kikuchi , Shinsuke Uno , Yasuko Kinoshita , Shigeyuki Iijima , Naoshi Fukushima , Masayuki Tsuchiya
- 申请人地址： JP Tokyo
- 专利权人： Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人： Chugai Seiyaku Kabushiki Kaisha
- 当前专利权人地址： JP Tokyo
- 代理机构： Foley & Lardner LLP
- 优先权： JP2003-381406 20031111
- 主分类号： C12P21/06
- IPC分类号： C12P21/06 ; C12N15/87 ; C12N5/02 ; C12N5/20 ; C12N1/20 ; C12N15/00 ; C07H21/04
摘要：
The present invention relates to humanized antibodies binding to CD47; diabodies binding to human CD47, characterized in that a disulfide bond exists between diabody-forming fragments; genes encoding any one of said antibodies; vectors containing said genes; host cells containing said vectors; processes for preparing antibodies comprising the step of culturing said host cells; and therapeutic agents for hematological disorders comprising said antibodies.
公开/授权文献
- US20120156724A1 HUMANIZED ANTI-CD47 ANTIBODY 公开/授权日：2012-06-21
信息查询
