发明授权
- 专利标题: Capsule of thermogenic cells for treating a metabolic disease
- 专利标题(中): 用于治疗代谢性疾病的生热细胞胶囊
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申请号: US12884587申请日: 2010-09-17
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公开(公告)号: US08858990B2公开(公告)日: 2014-10-14
- 发明人: Ouliana Ziouzenkova
- 申请人: Ouliana Ziouzenkova
- 申请人地址: US OH Columbus
- 专利权人: The Ohio State University
- 当前专利权人: The Ohio State University
- 当前专利权人地址: US OH Columbus
- 代理机构: MacMillan, Sobanski & Todd, LLC
- 主分类号: A61K9/48
- IPC分类号: A61K9/48 ; A01N63/00 ; A61K48/00 ; C12N15/00 ; C12N5/077 ; A61K9/50 ; C12N5/0775 ; A61K9/00 ; C07K14/245 ; A61K35/12
摘要:
Described herein are methods and devices for treating a metabolic disease that involve implanting a micro-device into a tissue of a subject having a metabolic disease. The micro-device includes a plurality of thermogenic cells encapsulated in a biocompatible capsule. The capsule includes a core to accommodate the plurality of thermogenic cells and a porous immunoprotective membrane that allows for metabolic interaction between the plurality of thermogenic cells and the tissue.
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