Invention Grant
- Patent Title: Diagnosis of malignant neoplasms using anti-Notch3 antibodies
- Patent Title (中): 使用抗Notch3抗体诊断恶性肿瘤
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Application No.: US13942421Application Date: 2013-07-15
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Publication No.: US08956811B2Publication Date: 2015-02-17
- Inventor: Kang Li , Sek Chung Fung , Zhengbin Yao
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech Inc.
- Current Assignee: Genentech Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Casimir Jones, S.C.
- Agent Tyler J. Sisk
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/18 ; C07K16/28 ; G01N33/50 ; G01N33/53 ; G01N33/574 ; G01N33/577 ; A61K39/00 ; A61K39/395
Abstract:
The present invention relates to novel antibodies that bind specifically to human Notch 3 and their use in the detection and/or diagnosis of Notch 3 related diseases, such as cancer. The present invention also includes nucleic acids encoding these novel antibodies, vectors and cell lines harboring the nucleic acids, and kits comprising the antibodies for use in the detection and diagnosis.
Public/Granted literature
- US20140057288A1 NOVEL ANTI-NOTCH3 ANTIBODIES AND THEIR USE IN THE DETECTION AND DIAGNOSIS OF DISEASE Public/Granted day:2014-02-27
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