Invention Grant
- Patent Title: Ruthenium catalysts and their use for asymmetric reduction of ketones
- Patent Title (中): 钌催化剂及其不对称还原酮的用途
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Application No.: US14313085Application Date: 2014-06-24
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Publication No.: US09029540B2Publication Date: 2015-05-12
- Inventor: Nizar Haddad , Heewon Lee , Bo Qu , Sonia Rodriguez , Chris Hugh Senanayake
- Applicant: Nizar Haddad , Heewon Lee , Bo Qu , Sonia Rodriguez , Chris Hugh Senanayake
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Usha R. Patel
- Main IPC: C07F15/00
- IPC: C07F15/00 ; C07D405/04 ; B01J31/22 ; C07D215/20 ; C07D209/04 ; C07D333/54 ; C07D307/79 ; C07C29/145 ; C07D231/56 ; B01J23/46 ; B01J31/24 ; C07C29/156 ; C07B53/00

Abstract:
Disclosed are novel ruthenium compounds of formula (Ia) and (Ib): wherein R1 and the moiety are defined herein. Also disclosed is a process for using these novel ruthenium compounds as catalysts for asymmetric hydrogenation and transfer hydrogenation of ketones with high reactivities and excellent selectivities.
Public/Granted literature
- US20150005500A1 NOVEL RUTHENIUM CATALYSTS AND THEIR USE FOR ASYMMETRIC REDUCTION OF KETONES Public/Granted day:2015-01-01
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