发明授权
- 专利标题： Fluorescent imaging with substituted cyanine dyes
- 专利标题（中）： 用取代花青染料进行荧光成像
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申请号： US13836202申请日： 2013-03-15
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公开(公告)号： US09089603B2公开(公告)日： 2015-07-28
- 发明人: Xinshe Xu , Daniel R. Draney , Mark Cradduck , Lael Cheung , Kousik Kundu , William M. Volcheck
- 申请人： LI-COR, INC.
- 申请人地址： US NE Lincoln
- 专利权人： LI-COR, INC.
- 当前专利权人： LI-COR, INC.
- 当前专利权人地址： US NE Lincoln
- 代理机构： Kilpatrick Townsend & Stockton LLP
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; A61K49/00 ; C09B23/01 ; C09B23/08 ; C09B69/00 ; G01N33/574 ; G01N33/58 ; C07F9/6561 ; C07K19/00 ; C08B37/08
摘要：
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented: wherein Q is a portion of a polymethine bridge: Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
公开/授权文献
- US20130280172A1 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES 公开/授权日：2013-10-24