发明授权
- 专利标题： Enzymatic encoding methods for efficient synthesis of large libraries
- 专利标题（中）： 用于高效合成大型文库的酶编码方法
-
申请号： US12095778申请日： 2006-12-01
-
公开(公告)号： US09574189B2公开(公告)日： 2017-02-21
- 发明人: Thomas Franch , Mikkel Dybro Lundorf , Søren Nyboe Jacobsen , Eva Kampmann Olsen , Anne Lee Andersen , Anette Holtmann , Anders Holm Hansen , Anders Malling Sørensen , Anne Goldbech , Daen de Leon , Ditte Kievsmose Kaldor , Frank Abildgaard Sløk , Gitte Nystrup Husemoen , Johannes Dolberg , Kim Birkebæ Jensen , Lene Pedersen , Mads Nørregaard-Madsen , Michael Anders Godskesen , Sanne Schrøder Glad , Søren Neve , Thomas Thisted , Tine Titilola Akinleminu Kronborg , Christian Klarner Sams , Jakob Felding , Per-Ola Freskgård , Alex Haahr Gouliaev , Henrik Pedersen
- 申请人： Thomas Franch , Mikkel Dybro Lundorf , Søren Nyboe Jacobsen , Eva Kampmann Olsen , Anne Lee Andersen , Anette Holtmann , Anders Holm Hansen , Anders Malling Sørensen , Anne Goldbech , Daen de Leon , Ditte Kievsmose Kaldor , Frank Abildgaard Sløk , Gitte Nystrup Husemoen , Johannes Dolberg , Kim Birkebæ Jensen , Lene Pedersen , Mads Nørregaard-Madsen , Michael Anders Godskesen , Sanne Schrøder Glad , Søren Neve , Thomas Thisted , Tine Titilola Akinleminu Kronborg , Christian Klarner Sams , Jakob Felding , Per-Ola Freskgård , Alex Haahr Gouliaev , Henrik Pedersen
- 申请人地址： DK Copenhagen
- 专利权人： Nuevolution A/S
- 当前专利权人： Nuevolution A/S
- 当前专利权人地址： DK Copenhagen
- 代理机构： Merchant & Gould P.C.
- 优先权： DK200501704 20051201
- 国际申请： PCT/DK2006/000685 WO 20061201
- 国际公布： WO2007/062664 WO 20070607
- 主分类号： C12N15/10
- IPC分类号： C12N15/10 ; C40B40/08 ; C40B50/04 ; C40B50/06
摘要：
Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
公开/授权文献
信息查询
IPC分类:
