- 专利标题： Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
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申请号： US14188647申请日： 2014-02-24
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公开(公告)号： US09789118B2公开(公告)日： 2017-10-17
- 发明人: David Weninger Barnes , Gregory Raymond Bebernitz , Kevin Clairmont , Scott Louis Cohen , Robert Edson Damon, II , Robert Francis Day , Stephanie Kay Dodd , Christoph Gaul , Hatice Belgin Gulgeze Efthymiou , Monish Jain , Rajeshri Ganesh Karki , Louise Clare Kirman , Kai Lin , Justin Yik Ching Mao , Tajesh Jayprakash Patel , Brian Kenneth Raymer , Su Liansheng
- 申请人： David Weninger Barnes , Gregory Raymond Bebernitz , Kevin Clairmont , Scott Louis Cohen , Robert Edson Damon, II , Robert Francis Day , Stephanie Kay Dodd , Christoph Gaul , Hatice Belgin Gulgeze Efthymiou , Monish Jain , Rajeshri Ganesh Karki , Louise Clare Kirman , Kai Lin , Justin Yik Ching Mao , Tajesh Jayprakash Patel , Brian Kenneth Raymer , Su Liansheng
- 申请人地址： CH Basel
- 专利权人： NOVARTIS AG
- 当前专利权人： NOVARTIS AG
- 当前专利权人地址： CH Basel
- 代理商 Joshua Roth
- 主分类号： C07D215/36
- IPC分类号： C07D215/36 ; C07D235/18 ; C07D263/57 ; C07D401/04 ; C07D401/12 ; C07D403/04 ; C07D405/04 ; C07D413/12 ; C07D471/04 ; C07D513/04 ; A61K31/542 ; A61K31/4184 ; A61K9/00 ; A61K9/08 ; A61K9/107 ; C12N9/00 ; A61K31/404 ; A61K31/423 ; A61K31/496 ; A61K31/5377 ; A61K45/06 ; C07D209/24 ; C07D235/08 ; C07D235/12 ; C07D235/16 ; C07D235/30 ; C07D405/14
摘要：
The present invention provides compounds of formula (IV); or pharmaceutically acceptable salts thereof, wherein the variables are defined as herein. The present invention provides a method for manufacturing the compounds of formula (IV), their therapeutic uses, combinations with other of pharmacologically active agents, and a pharmaceutical compositions.
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