- 专利标题： L-arabinose isomerase variants with improved conversion activity and method for production of D-tagatose using them
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申请号： US15413960申请日： 2017-01-24
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公开(公告)号： US09896705B2公开(公告)日： 2018-02-20
- 发明人: In Seok Oh , Chang Gyeom Kim , Seung Hyun Cho , Seong Bo Kim , Yang Hee Kim , Kyong Yeon Cho , Sung Jae Yang , Jin Ha Kim
- 申请人： CJ Cheiljedang Corporation
- 申请人地址： KR Seoul
- 专利权人： CJ CHEILJEDANG CORPORATION
- 当前专利权人： CJ CHEILJEDANG CORPORATION
- 当前专利权人地址： KR Seoul
- 代理机构： Swanson & Bratschun, L.L.C.
- 主分类号： C12P19/02
- IPC分类号： C12P19/02 ; C12P19/24 ; C12N1/20 ; C12N9/90 ; C12N15/77
摘要：
The present invention relates to the development of an L-arabinose isomerase variant from Thermotoga neapolitana DSM 5068, which is a kind of thermophile, on the basis of protein molecular modeling. Moreover, the present invention relates to a method of producing D-tagatose from D-galactose by using the enzyme or a microorganism of the genus Corynebacterium expressing the enzyme.
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