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1.发明授权公开(公告)号：US11053524B2
公开(公告)日：2021-07-06
申请号：US16246082
申请日：2019-01-11
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Kyoung Min Lee , Hee Kyoung Jung , Young Lyeol Yang , Hye Won Um , Chang Gyeom Kim , Hong Xian Li , Su Jin Park , Jong Hyun Yoon , Baek Seok Lee , Sun Young Lee
Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine, in which the microorganism is modified to have enhanced NCgl2522 activity, thereby producing putrescine in a high yield, and a method for producing putrescine using the microorganism.
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2.发明申请MICROORGANISMS OF CORYNEBACTERIUM WHICH CAN UTILIZE XYLOSE AND METHOD FOR PRODUCING L-LYSINE USING SAME 审中-公开可以利用木糖醇的康乃馨的微生物和使用其生产L-赖氨酸的方法公开(公告)号：US20160040200A1
公开(公告)日：2016-02-11
申请号：US14923825
申请日：2015-10-27
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Yeon Rah , Lan Huh , Chang Gyeom Kim , Kwang Ho Lee , Jun Ok Moon , Kyung Han Lee , Jin Seok Sung , Hyung Joon Kim
CPC classification number: C12P13/08 , C12N9/1205 , C12N9/92 , C12Y207/01017 , C12Y503/01005 , Y02P20/52
Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。
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3.发明授权公开(公告)号：US10221433B2
公开(公告)日：2019-03-05
申请号：US14778383
申请日：2014-02-25
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Kyoung Min Lee , Hee Kyoung Jung , Young Lyeol Yang , Hye Won Um , Chang Gyeom Kim , Hong Xian Li , Su Jin Park , Jong Hyun Yoon , Baek Seok Lee , Sun Young Lee
Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine, in which the microorganism is modified to have enhanced NCgl2522 activity, thereby producing putrescine in a high yield, and a method for producing putrescine using the microorganism.
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4.发明申请MICROORGANISMS OF CORYNEBACTERIUM WHICH CAN UTILIZE XYLOSE AND METHOD FOR PRODUCING L-LYSINE USING SAME 有权可以利用木糖醇的康乃馨的微生物和使用其生产L-赖氨酸的方法公开(公告)号：US20140377816A1
公开(公告)日：2014-12-25
申请号：US14371653
申请日：2013-01-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Yeon Rah , Lan Huh , Chang Gyeom Kim , Kwang Ho Lee , Jun Ok Moon , Kyung Han Lee , Jin Seok Sung , Hyung Joon Kim
IPC: C12P13/08
CPC classification number: C12P13/08 , C12N9/1205 , C12N9/92 , C12Y207/01017 , C12Y503/01005 , Y02P20/52
Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。
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公开(公告)号：US09896705B2
公开(公告)日：2018-02-20
申请号：US15413960
申请日：2017-01-24
Applicant: CJ Cheiljedang Corporation
Inventor： In Seok Oh , Chang Gyeom Kim , Seung Hyun Cho , Seong Bo Kim , Yang Hee Kim , Kyong Yeon Cho , Sung Jae Yang , Jin Ha Kim
Abstract: The present invention relates to the development of an L-arabinose isomerase variant from Thermotoga neapolitana DSM 5068, which is a kind of thermophile, on the basis of protein molecular modeling. Moreover, the present invention relates to a method of producing D-tagatose from D-galactose by using the enzyme or a microorganism of the genus Corynebacterium expressing the enzyme.
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Patent Agency Ranking
6.发明授权公开(公告)号：US09534240B2
公开(公告)日：2017-01-03
申请号：US14370721
申请日：2013-01-03
Applicant: CJ Cheiljedang Corporation
Inventor： Yong Uk Shin , So Young Kim , In Kyung Heo , Ju Eun Kim , Sung Kwang Son , Jae Hee Lee , Ji Hyun Lee , Chang Gyeom Kim
CPC classification number: C12P17/12 , C12N9/0022 , C12N9/1085 , C12N15/52 , C12N15/62 , C12N15/70 , C12Y104/03016 , C12Y205/01072 , Y02P20/52
Abstract: The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method for producing quinolinic acid using the same.
Abstract translation: 本发明涉及表达通过接头连接的L-天冬氨酸氧化酶和喹啉酸合成酶的融合蛋白的喹啉酸生产重组微生物及使用其的喹啉酸的制备方法。
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公开(公告)号：US09938515B2
公开(公告)日：2018-04-10
申请号：US14786510
申请日：2014-04-23
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Young Moon Cho , Chang Gyeom Kim , Baek Seok Lee
IPC: C12N9/90 , C12N15/00 , C12N1/20 , C12P21/06 , C12P21/04 , C12P19/02 , C07H21/04 , C12P19/24 , C12N11/00
Abstract: The present invention relates to: a D-psicose 3-epimerase mutant from Agrobacterium tumefaciens with improved thermal stability; a recombinant vector comprising a gene encoding the mutant; and a microorganism comprising the mutant. In addition, the present invention relates to a method for producing D-psicose by using the epimerase mutant or the microorganism.
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8.发明授权L-arabinose isomerase variants with improved conversion activity and method for production of D-tagatose using them 有权具有改善的转化活性的L-阿拉伯糖异构酶变体和使用它们生产D-塔格糖的方法公开(公告)号：US09593321B2
公开(公告)日：2017-03-14
申请号：US15112232
申请日：2014-04-25
Applicant: CJ Cheiljedang Corporation
Inventor： In Seok Oh , Chang Gyeom Kim , Seung Hyun Cho , Seong Bo Kim , Yang Hee Kim , Kyong Yeon Cho , Sung Jae Yang , Jin Ha Kim
Abstract: The present invention relates to the development of an L-arabinose isomerase variant from Thermotoga neapolitana DSM 5068, which is a kind of thermophile, on the basis of protein molecular modeling. Moreover, the present invention relates to a method of producing D-tagatose from D-galactose by using the enzyme or a microorganism of the genus Corynebacterium expressing the enzyme.
Abstract translation: 本发明涉及在蛋白质分子模型的基础上从Thermotoga neapolitana DSM 5068开发的L-阿拉伯糖异构酶变体，其是一种嗜热菌。 此外，本发明涉及通过使用表达该酶的棒状杆菌属的酶或微生物从D-半乳糖生产D-塔格糖的方法。
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公开(公告)号：US09399784B2
公开(公告)日：2016-07-26
申请号：US14923825
申请日：2015-10-27
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Yeon Rah , Lan Huh , Chang Gyeom Kim , Kwang Ho Lee , Jun Ok Moon , Kyung Han Lee , Jin Seok Sung , Hyung Joon Kim
CPC classification number: C12P13/08 , C12N9/1205 , C12N9/92 , C12Y207/01017 , C12Y503/01005 , Y02P20/52
Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
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10.发明授权Microorganisms of Corynebacterium which can utilize xylose and method for producing L-lysine using same 有权可以利用木糖的棒状杆菌的微生物和使用它们生产L-赖氨酸的方法公开(公告)号：US09200300B2
公开(公告)日：2015-12-01
申请号：US14371653
申请日：2013-01-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Yeon Rah , Lan Huh , Chang Gyeom Kim , Kwang Ho Lee , Jun Ok Moon , Kyung Han Lee , Jin Seok Sung , Hyung Joon Kim
CPC classification number: C12P13/08 , C12N9/1205 , C12N9/92 , C12Y207/01017 , C12Y503/01005 , Y02P20/52
Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.
Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。
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