Invention Application
WO2005013914A3 HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN
审中-公开
用于治疗疼痛的钠或钙通道阻断剂的异喹啉基苯基衍生物
- Patent Title: HETEROARYLAMINOSULFONYLPHENYL DERIVATIVES FOR USE AS SODIUM OR CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN
- Patent Title (中): 用于治疗疼痛的钠或钙通道阻断剂的异喹啉基苯基衍生物
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Application No.: PCT/US2004025827Application Date: 2004-08-09
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Publication No.: WO2005013914A3Publication Date: 2005-07-21
- Inventor: GONZALES JESUS E III , TERMIN ANDREAS P , MARTINBOROUGH ESTHER , ZIMMERMAN NICOLE
- Applicant: VERTEX PHARMA , GONZALES JESUS E III , TERMIN ANDREAS P , MARTINBOROUGH ESTHER , ZIMMERMAN NICOLE
- Assignee: VERTEX PHARMA,GONZALES JESUS E III,TERMIN ANDREAS P,MARTINBOROUGH ESTHER,ZIMMERMAN NICOLE
- Current Assignee: VERTEX PHARMA,GONZALES JESUS E III,TERMIN ANDREAS P,MARTINBOROUGH ESTHER,ZIMMERMAN NICOLE
- Priority: US49365903 2003-08-08; US58471704 2004-07-01
- Main IPC: A61K31/513
- IPC: A61K31/513 ; A61K31/517 ; A61K31/522 ; A61K31/5377 ; A61K31/5415 ; C07C311/46 ; C07C311/51 ; C07D209/80 ; C07D209/92 ; C07D213/76 ; C07D231/38 ; C07D231/42 ; C07D237/20 ; C07D237/22 ; C07D239/42 ; C07D239/46 ; C07D239/52 ; C07D239/54 ; C07D239/545 ; C07D239/69 ; C07D241/22 ; C07D261/16 ; C07D263/50 ; C07D277/52 ; C07D277/82 ; C07D285/12 ; C07D285/125 ; C07D285/135 ; C07D295/26 ; C07D401/12 ; C07D403/12 ; C07D405/12 ; C07D405/14 ; C07D407/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D417/14 ; C07D513/04 ; C07C311/44
Abstract:
The present invention relates to compounds such as those of formula (I-A) inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, such as pain.
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