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1.发明公开USE OF NORDIHYDROGUAIARETIC ACID DERIVATIVES IN THE TREATMENT OF DRUG RESISTANT CANCER, VIRAL AND MICROBIAL INFECTION 审中-公开NORDIHYDROGUAJARETSÄUREDERIVATEN在治疗药物产生耐药性的癌症和病毒性和细菌感染USE
公开(公告)号：EP1848418A2
公开(公告)日：2007-10-31
申请号：EP05816163.9
申请日：2005-10-06
发明人： HUANG, Ru Chih C., Johns Hopkins University, Department of Biology , HWU, Jih-Ru c/o Department of chemistry , HSU, Ming-Hua c/o Department of Chemistry , MOLD, David E. Johns Hopkins University, Department of Biology , LEE, Yuan C. Johns Hopkins University, Department of Biology , CHANG, Chih-Chuan Johns Hopkins University, Department of Biology
IPC分类号： A61K31/192
CPC分类号： A61K31/192 , A61K31/09 , A61K31/24 , A61K31/337 , A61K31/475 , A61K31/7034 , A61K31/704 , A61K45/06 , C07H15/18 , A61K2300/00
摘要： Compositions and methods for using nordihydroguaiaretic acid (NDGA) derivatives for preventing the expression of MDR-1 gene and the synthesis of PgP protein or reversing multiple drug resistance in cells, and for using NDGA derivatives in combination with additional chemotherapeutic agents to treat drug resistant cancer and infections.
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2.发明公开USE OF NORDIHYDROGUAIARETIC ACID DERIVATIVES IN THE TREATMENT OF DRUG RESISTANT CANCER, VIRAL AND MICROBIAL INFECTION 审中-公开NORDIHYDROGUAJARETSÄUREDERIVATEN在治疗药物产生耐药性的癌症和病毒性和细菌感染USE
公开(公告)号：EP1848418A4
公开(公告)日：2010-09-08
申请号：EP05816163
申请日：2005-10-06
申请人： UNIV JOHNS HOPKINS , MOLD DAVID E , LEE YUAN C , CHANG CHIH CHUAN
发明人： HUANG RU CHIH C , HWU JIH-RU , HSU MING-HUA , MOLD DAVID E , LEE YUAN C , CHANG CHIH-CHUAN
IPC分类号： A61K31/7004 , A61K31/09 , A61K31/223 , A61K31/24 , A61K31/337 , A61K31/475 , A61K31/7034 , A61K31/704 , A61K45/06 , A61P31/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P33/00 , A61P35/00 , C07C229/08 , C07C229/12 , C07H7/04 , C07H15/203
CPC分类号： A61K31/192 , A61K31/09 , A61K31/24 , A61K31/337 , A61K31/475 , A61K31/7034 , A61K31/704 , A61K45/06 , C07H15/18 , A61K2300/00
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