公开(公告)号：EP2376462A1

公开(公告)日：2011-10-19

申请号：EP09775056.6

申请日：2009-12-16

申请人： Abbott Laboratories

发明人： FROST, Jennifer, M. ,  LATSHAW, Steven, P. ,  DART, Michael, J. ,  CARROLL, William, A. ,  PEREZ-MEDRANO, Arturo ,  KOLASA, Teodozyj ,  PATEL, Meena ,  NELSON, Derek, W. ,  LI, Tongmei ,  PEDDI, Sridhar ,  WANG, Xueqing ,  LIU, Bo

IPC分类号： C07D277/46 ,  C07D417/12 ,  C07D513/04 ,  A61K31/426 ,  A61K31/427 ,  A61K31/428 ,  A61P3/04 ,  A61P3/10 ,  A61P9/00 ,  A61P11/00 ,  A61P29/00 ,  A61P35/00

CPC分类号： C07D417/12 ,  C07D277/46 ,  C07D513/04

摘要： Disclosed herein are cannabinoid receptor ligands of formula (I) wherein L
1 , A
1 , R
1g , z, R
2 , R
3 , and R
4 are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.

公开(公告)号：EP2274306A1

公开(公告)日：2011-01-19

申请号：EP09719609.1

申请日：2009-03-11

申请人： Abbott Laboratories

发明人： KOLASA, Teodozyi ,  FROST, Jennifer, M. ,  PATEL, Meena, V. ,  LATSHAW, Steven, P. ,  PEREZ-MEDRANO, Arturo ,  WANG, Xueqing ,  TIETJE, Karin, Rose, Marie ,  PEDDI, Sridhar ,  CARROLL, William, A.

IPC分类号： C07D417/06 ,  A61K31/426

CPC分类号： C07D417/06

摘要： Disclosed herein are compounds of formula (I) wherein R
1 , R
2 , R
3 , R
25a , R
26a , X, and n are as defined in the specification. Pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions are also described.

公开(公告)号：EP2219629A1

公开(公告)日：2010-08-25

申请号：EP08837396.4

申请日：2008-10-08

申请人： Abbott Laboratories

发明人： CARROLL, William A. ,  PEDDI, Sridhar ,  PEREZ-MEDRANO, Arturo ,  DART, Michael J. ,  NELSON, Derek W. ,  LI, Tongmei ,  LIU, Bo ,  KOLASA, Teodozyj ,  FROST, Jennifer ,  WANG, Xueqing ,  LATSHAW, Steven, P.

IPC分类号： A61K31/015 ,  A61P43/00

CPC分类号： C07D405/06 ,  C07D405/14 ,  C07D413/06 ,  C07D413/14 ,  C07D417/06 ,  C07D417/14

摘要： The present invention relates compounds of formula (I), as defined in the specification, pharmaceutical compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and pharmaceutical compositions.

摘要翻译： 本发明涉及如说明书中所定义的式（I）化合物，包含此类化合物的药物组合物，以及使用此类化合物和药物组合物治疗病症和障碍的方法。

公开(公告)号：EP2331516B1

公开(公告)日：2013-03-13

申请号：EP09791365.1

申请日：2009-08-11

申请人： ABBOTT LABORATORIES

发明人： CARROLL, William, A. ,  DART, Michael, J. ,  FROST, Jennifer, M. ,  KOLASA, Teodozyj ,  LATSHAW, Steven, P. ,  LIU, Bo ,  PATEL, Meena, V. ,  PEREZ-MEDRANO, Arturo ,  WANG, Xueqing

IPC分类号： C07D261/14 ,  C07D407/06 ,  C07D417/06 ,  C07D285/135 ,  A61K31/433 ,  A61P29/00

CPC分类号： C07D261/14 ,  C07D285/135 ,  C07D407/06 ,  C07D417/06

公开(公告)号：EP2331516A1

公开(公告)日：2011-06-15

申请号：EP09791365.1

申请日：2009-08-11

申请人： ABBOTT LABORATORIES

发明人： CARROLL, William, A. ,  DART, Michael, J. ,  FROST, Jennifer, M. ,  KOLASA, Teodozyj ,  LATSHAW, Steven, P. ,  LIU, Bo ,  PATEL, Meena, V. ,  PEREZ-MEDRANO, Arturo ,  WANG, Xueqing

IPC分类号： C07D261/14 ,  C07D407/06 ,  C07D417/06 ,  C07D285/135 ,  A61K31/433 ,  A61P29/00

CPC分类号： C07D261/14 ,  C07D285/135 ,  C07D407/06 ,  C07D417/06

摘要： Disclosed herein are cannabinoid receptor ligands of formula (I), wherein Y, X
1 , X
2 , X
3 , R
1 , and R
2 are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.