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公开(公告)号：EP4129320A1
公开(公告)日：2023-02-08
申请号：EP22180817.3
申请日：2016-02-19
申请人： Compugen Ltd.
发明人： WHITE, Mark , KUMAR, Sandeep , CHAN, Christopher , LIANG, Spencer , STAPELTON, Lance , DRAKE, Andrew W. , GOZLAN, Yosi , VAKNIN, Ilan , SAMEAH-GREENWALD, Shirley , DASSA, Liat , TIRAN, Zohar , COJOCARU, Gad S. , PRESTA, Leonard , THEOLIS, Richard
IPC分类号： A61K38/00 , C07K14/00 , C07K16/28 , C12N15/113 , A61P35/00
摘要： The present invention is directed to anti-PVRIG antibodies and methods of using same.
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2.发明授权Antibody specific for heparanase splice variant T5 and its use. 有权Heparanase Spice-Variante T5 spezifischerAntikörperund dessen Verwendung。
公开(公告)号：EP2507265B1
公开(公告)日：2016-05-11
申请号：EP10805501.3
申请日：2010-11-30
申请人： Compugen Ltd.
发明人： SHEMESH, Ronen , AYALON-SOFFER, Michal , LEVINE, Zurit , NEMZER, Sergey , ZEKHARYA, Tomer , COJOCARU, Gad S. , BARASH, Uri , ILAN, Neta , VLODAVSKY, Israel , HECHT, Iris
IPC分类号： C07K16/40 , C07K16/30 , C12N9/24 , C12N15/113
CPC分类号： C07K16/30 , C07K16/40 , C12N9/2402 , C12N15/1137 , C12N2310/11 , C12N2310/12 , C12N2310/14 , C12Y302/01166
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公开(公告)号：EP3295951B1
公开(公告)日：2020-04-22
申请号：EP17192325.3
申请日：2016-02-19
申请人： Compugen Ltd.
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公开(公告)号：EP2240601B1
公开(公告)日：2016-10-12
申请号：EP08867219.1
申请日：2008-12-01
申请人： Compugen Ltd.
发明人： KINAR, Yaron , BEIMAN, Merav , MONTIA, Eve , WALLACH, Shira , PERGAM, Tania , NOVIK, Amit , SAMEAH-GREENWALD, Shirley , COJOCARU, Gad S. , COHEN-DAYAG, Anat , FURMAN, Yael
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/136 , C12Q2600/142 , C12Q2600/156 , C12Q2600/158 , G01N33/6893 , G01N2800/347 , G01N2800/60
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5.发明公开
公开(公告)号：EP3043819A1
公开(公告)日：2016-07-20
申请号：EP14844096.9
申请日：2014-09-11
申请人： Compugen Ltd.
发明人： LEVINE, Zurit , ROTMAN, Galit , DASSA, Liat , LEVY, Ofer , COJOCARU, Gad S. , TOPORIK, Amir , KLIGER, Yossef , POW, Andrew , LIANG, Spencer
IPC分类号： A61K39/395 , C07K16/18 , G01N33/574 , C07K16/30 , G01N33/564 , G01N33/569
CPC分类号： C07K16/28 , A61K31/664 , A61K38/00 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/5154 , C07K14/705 , C07K16/2803 , C07K16/2818 , C07K16/30 , C07K2317/21 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/30 , G01N33/564 , G01N33/57492 , G01N2800/24 , G01N2800/26 , G01N2800/50 , G01N2800/52 , G01N2800/54 , G01N2800/56 , Y02A50/41 , Y02A50/412 , Y02A50/416 , Y02A50/421 , Y02A50/466 , Y02A50/491 , Y02A50/492 , Y02A50/55 , Y02A50/58 , A61K31/675 , A61K2039/5152 , A61K38/1774
摘要： The present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same, for modulating (antagonizing or agonizing) one or more of the effects of VSTM5 expression on immunity. More specifically, the present invention relates to VSTM5-specific antibodies, antibody fragments, and VSTM5 polypeptides, conjugates and compositions comprising same for treating and aiding in the diagnosis of cancer, infectious diseases and immune related diseases, e.g., those associated with aberrant (higher or lower than normal) VSTM5 expression by diseased and/or immune cells and/or aberrant (increased or reduced) VSTM5-mediated effects on immunity.
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公开(公告)号：EP3971211A1
公开(公告)日：2022-03-23
申请号：EP21188908.4
申请日：2016-07-13
申请人： Compugen Ltd.
发明人： DICKEN, Yosef , DASSA, Liat , NOVIK, Amit , TOPORIK, Amir , COJOCARU, Gad S. , KLIGER, Yossef , BENITA, Yair , LEVY, Ofer , VAKNIN, Ilan , MACHLENKIN, Arthur , HECHT, Iris , KIM, Jungmin , POW, Andrew , DRAKE, Andrew W.
IPC分类号： C07K16/28 , A61K39/395 , A61P35/00
摘要： According to at least some embodiments of the present invention is directed to anti-HIDE1 antibodies and polypeptides and methods of using same.
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公开(公告)号：EP3258951B1
公开(公告)日：2020-01-29
申请号：EP16707603.3
申请日：2016-02-19
申请人： Compugen Ltd.
发明人： WHITE, Mark , KUMAR, Sandeep , CHAN, Christopher , LIANG, Spencer , STAPLETON, Lance , DRAKE, Andrew W. , GOZLAN, Yosi , VAKNIN, IIan , SAMEAH-GREENWALD, Shirley , DASSA, Liat , TIRAN, Zohar , COJOCARU, Gad S. , PRESTA, Leonard , THEOLIS, Richard
IPC分类号： A61K38/00 , C07K14/00 , C07K16/28 , C12N15/113
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公开(公告)号：EP3258951A1
公开(公告)日：2017-12-27
申请号：EP16707603.3
申请日：2016-02-19
申请人： Compugen Ltd.
发明人： WHITE, Mark , KUMAR, Sandeep , CHAN, Christopher , LIANG, Spencer , STAPLETON, Lance , DRAKE, Andrew W. , GOZLAN, Yosi , VAKNIN, IIan , SAMEAH-GREENWALD, Shirley , DASSA, Liat , TIRAN, Zohar , COJOCARU, Gad S. , PRESTA, Leonard , THEOLIS, Richard
IPC分类号： A61K38/00 , C07K14/00 , C07K16/28 , C12N15/113
摘要： The present invention is directed to anti-PVRIG antibodies and methods of using same.
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公开(公告)号：EP2403958A1
公开(公告)日：2012-01-11
申请号：EP09787432.5
申请日：2009-03-01
申请人： Compugen Ltd.
发明人： KINAR, Yaron , BEIMAN, Merav , MONTIA, Eve , WALLACH, Shira , PERGAM, Tania , NOVIK, Amit , SAMEAH-GREENWALD, Shirley , COJOCARU, Gad S. , COHEN-DAYAG, Anat , FURMAN, Yael
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/118 , C12Q2600/142 , C12Q2600/158 , C12Q2600/16 , G01N33/6893 , G01N2800/347 , G01N2800/52 , Y10T436/143333
摘要： The present invention relates to means and methods for predicting the onset of renal injury based on measuring the expression of polynucleotides and proteins, particularly on measuring the expression of sets of polynucelotides and/or proteins, and to kits utilizing same. The present invention discloses novel polynucleotide varinats and proteins encoded therefrom, and sets comprising the novel polynucleotides, and known genes the expression of which is indicative of renal injury.
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公开(公告)号：EP3978929A1
公开(公告)日：2022-04-06
申请号：EP21188559.5
申请日：2016-02-19
申请人： Compugen Ltd.
发明人： WHITE, Mark , KUMAR, Sandeep , CHAN, Christopher , LIANG, Spencer , STAPELTON, Lance , DRAKE, Andrew W. , GOZLAN, Yosi , VAKNIN, Ilan , SAMEAH-GREENWALD, Shirley , DASSA, Liat , TIRAN, Zohar , COJOCARU, Gad S. , LEVY, Ofer , MACHLENKIN, Arthur , TOPORIK, Amir , KLIGER, Yossef , NEMZER, Sergey , NOVIK, Amit , BENITA, Yair
摘要： The present invention is directed to PVRIG polypeptides and their uses.
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