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公开(公告)号：EP2255014A4
公开(公告)日：2011-05-18
申请号：EP09711261
申请日：2009-02-12
发明人： BJORNSON KEITH , BIBILLO AREK , SEBO LUBOMIR
CPC分类号： C12Q1/6874 , C12Q2527/127 , C12Q2527/113
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公开(公告)号：EP2274446A4
公开(公告)日：2011-04-20
申请号：EP09755191
申请日：2009-03-30
发明人： BJORNSON KEITH , LEE HAROLD , KORLACH JONAS , TURNER STEPHEN , BIBILLO AREK , CHRISTIANS FRED , EMIG ROBIN , HE MOLLY , PARK INSIL , JIA LEI , FEDOROV ANDREI , LYLE JOHN M
CPC分类号： C12Q1/6869 , C12Q1/6874 , C12Q2527/125 , C12Q2527/119 , C12Q2527/101 , C12Q2565/1015 , C12Q2527/137 , C12Q2521/101
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3.发明公开GENERATION OF MODIFIED POLYMERASES FOR IMPROVED ACCURACY IN SINGLE MOLECULE SEQUENCING 有权单分子测序法提高修饰聚合物的生成精度
公开(公告)号：EP2271751A4
公开(公告)日：2011-09-14
申请号：EP09755183
申请日：2009-03-30
发明人： CLARK SONYA , BIBILLO AREK , PELUSO PAUL , CHRISTIANS FRED , HE MOLLY , PARK INSIL , LEE HAROLD , BJORNSON KEITH , JIA LEI , EMIG ROBIN
CPC分类号： C12N9/1252 , C12Q1/6844 , C12Q1/6869 , C12Q2521/101
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公开(公告)号：EP1963536A4
公开(公告)日：2010-03-03
申请号：EP06848948
申请日：2006-12-21
发明人： HANZEL DAVID K , OTTO GEOFF , MURPHY DEVON , PELUSO PAUL , PHAM THANG , RANK DAVID R , MITSIS PAUL , CHRISTIANS FRED C , BIBILLO AREK , PARK INSIL , CLARK SONYA , LYLE JOHN
IPC分类号： C12Q1/68
CPC分类号： C12N9/1252 , C07K2319/20 , C12P19/34 , C12Q1/6827 , C12Q1/6869 , C12Y207/07007 , Y02P20/52
摘要： Compositions that include polymerases with features for improving entry of nucleotide analogues into active site regions and for coordinating with the nucleotide analogues in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided.
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5.发明公开POLYMERASE ENZYMES AND REAGENTS FOR ENHANCED NUCLEIC ACID SEQUENCING 审中-公开聚合酶及试剂高级NUKEINSÄURESEQUENZIERUNG
公开(公告)号：EP2089517A4
公开(公告)日：2010-10-20
申请号：EP07867267
申请日：2007-10-22
发明人： RANK DAVID R , BIBILLO AREK , HANZEL DAVID K , PELUSO PAUL , WEGENER JEFF
CPC分类号： C12N9/1252 , C12P19/34
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公开(公告)号：EP1937702A4
公开(公告)日：2010-08-11
申请号：EP06815834
申请日：2006-09-28
发明人： XU YUE , WEGENER JEFFEY , BIBILLO AREK
CPC分类号： C07H19/10 , C07H21/00 , C12Q1/6869 , C12Q2533/101 , C12Q2525/117 , C12Q2525/101
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