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公开(公告)号:EP3409765B1
公开(公告)日:2021-08-04
申请号:EP18185054.6
申请日:2010-06-22
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公开(公告)号:EP3319987B1
公开(公告)日:2021-05-05
申请号:EP16821779.2
申请日:2016-06-02
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公开(公告)号:EP3706780A1
公开(公告)日:2020-09-16
申请号:EP18875439.4
申请日:2018-11-02
申请人: Codexis, Inc.
发明人: NAZOR, Jovana , YANG, Jie , BANERJEE, Goutami , ZHANG, Xiyun , RIGGINS, James, Nicholas , MILCZEK, Erika, M. , MOORE, Jeffrey, C.
IPC分类号: A61K38/45 , C07K14/36 , C07K14/745 , C12N9/10
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公开(公告)号:EP3645711A1
公开(公告)日:2020-05-06
申请号:EP18824385.1
申请日:2018-06-19
申请人: Codexis, Inc.
发明人: MILLER, Mathew, G. , CHNG, Chinping , ALVIZO, Oscar , MAYO, Melissa, Ann , RIGGINS, James, Nicholas , YI, Xiang , PENFIELD, Jonathan, S. , HUISMAN, Gjalt, W.
IPC分类号: C12N9/12
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公开(公告)号:EP3638688A1
公开(公告)日:2020-04-22
申请号:EP18818898.1
申请日:2018-05-23
申请人: Codexis, Inc.
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公开(公告)号:EP3579867A1
公开(公告)日:2019-12-18
申请号:EP18750620.9
申请日:2018-02-12
申请人: Codexis, Inc.
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公开(公告)号:EP3565893A1
公开(公告)日:2019-11-13
申请号:EP18736330.4
申请日:2018-01-04
申请人: Codexis, Inc.
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公开(公告)号:EP3469088A1
公开(公告)日:2019-04-17
申请号:EP17810674.6
申请日:2017-04-19
申请人: Codexis, Inc.
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公开(公告)号:EP3023494B1
公开(公告)日:2018-11-28
申请号:EP15199731.9
申请日:2009-06-11
申请人: Codexis, Inc.
CPC分类号: C12N15/102 , C12N15/1031 , C12N15/1093 , C40B40/06 , C40B50/06
摘要: The present disclosure relates to methods for generating libraries of polynucleotide variants comprising defined nucleotide differences relative to a reference polynucleotide.
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10.
公开(公告)号:EP3224354A4
公开(公告)日:2018-05-16
申请号:EP15864252
申请日:2015-11-24
申请人: CODEXIS INC
发明人: ALVIZO OSCAR , MAYO MELISSA ANN , MOORE JEFFREY C
IPC分类号: C12N9/08
CPC分类号: C12N9/0028 , C07K14/195 , C12P13/001
摘要: The present application provides engineered polypeptides having imine reductase activity, polynucleotides encoding the engineered imine reductases, host cells capable of expressing the engineered imine reductases, and methods of using these engineered polypeptides with a range of ketone and amine substrate compounds to prepare secondary and tertiary amine product compounds.
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