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    LED DENSITOMETER FOR MICROTITER PLATE
    92.
    发明公开
    LED DENSITOMETER FOR MICROTITER PLATE 审中-公开
    用于微型平板的LED DICHTEMESSER

    公开(公告)号：EP2454579A4

    公开(公告)日：2012-12-05

    申请号：EP10800172

    申请日：2010-07-16

    Applicant: GOLD STANDARD DIAGNOSTICS CORP ,  PRAET PETER VAN

    Inventor： VAN PRAET PETER

    IPC: G01N21/25

    CPC classification number: G01N21/00 ,  G01N21/253 ,  G01N2201/0446 ,  G01N2201/0453 ,  G01N2201/0627 ,  G01N2201/10

    Abstract: Light emitting diodes (LEDs) are mounted in an array to an upper structure overlying a lower structure with a plurality of light detectors thereon. Each LED is configured to overlie a separate detector. Each LED emits light at a frequency relevant for measuring optical density of a specimen. LEDs having different frequencies are included within the LED array. A corresponding array of detectors is also provided, mounted to the lower structure. Spacing between adjacent LEDs and between adjacent detectors match a spacing between wells in a microtiter plate. Spacing between the lower structure and the upper structure supporting the LEDs is sufficient for the microtiter plate to fit between. Circuitry sequentially fires individual LEDs and gathers optical density data through the detectors for specimens in the wells of the microtiter plate. The structures are then moved to a next adjacent well position on the microtiter plate and the process repeated.

    MASKING TO PREVENT OVEREXPOSURE AND LIGHT SPILLAGE IN MICROARRAY SCANNING
    95.
    发明公开
    MASKING TO PREVENT OVEREXPOSURE AND LIGHT SPILLAGE IN MICROARRAY SCANNING 审中-公开
    面具预防过度​​曝光和光扩散的微阵列扫描

    公开(公告)号：EP1960210A2

    公开(公告)日：2008-08-27

    申请号：EP06838952.7

    申请日：2006-12-04

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： CHU, Daniel Y.

    IPC: B41J15/14

    CPC classification number: G01N21/253 ,  G01N2201/0446 ,  G01N2201/1042

    Abstract: Scanning of a microarray is performed through a mask that exposes a plurality, but not all, of the sites of the microarray, and either the mask is movable relative to the microarray or the microarray is movable relative to the mask, or both. The mask is useful as a means of restricting the illumination of sites on the microarray to those that can be illuminated while the scan head is traveling at a steady, target velocity, blocking the passage of light between the scan head and the microarray at those points in the scan head trajectory where the scan head is either accelerating or decelerating. The mask is also useful for reducing background noise in the microarray image by preventing light spillage to sites adjacent to those being scanned.

    APPARATUS AND METHOD FOR THE CALIBRATION AND QUALITY CONTROL OF A SPECTROPHOTOMETER
    99.
    发明授权
    APPARATUS AND METHOD FOR THE CALIBRATION AND QUALITY CONTROL OF A SPECTROPHOTOMETER 失效
    设备和方法用于校准和质量控制分光光度计

    公开(公告)号：EP0542913B1

    公开(公告)日：1996-05-22

    申请号：EP91916534.0

    申请日：1991-08-07

    Applicant: MACRI, James N. ,  COOK, Edward J.

    Inventor： MACRI, James N. ,  COOK, Edward J.

    IPC: G01J1/02 ,  G01N21/27

    CPC classification number: G01N21/274 ,  G01N2201/0446 ,  G01N2201/13

    Abstract: An apparatus for the calibration and quality assurance of a multichannel spectrophotometer, particularly an ELISA spectrophotometer, comprises film selectively exposed in the presence of a color to produce a series of filters (columns 3-10) having a known first color and linearly increasing optical density. The response of the spectrophotometer is measured against the known color and linearly increasing optical density. Additional filters (columns 11-12) of at least one additional color permit checking the color response of the spectrophotometer. An algorithm determines whether the response conforms to predetermined conditions. An output is produced to provide a record of the calibration and quality assurance of the spectrophotometer. The invention has particular utility for conducting calibration and quality assurance of ELISA spectrophotometers used in clinical laboratory screening for infectious diseases, such as Hepatitis B and the AIDS viruses.

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