利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

514 条记录 (耗时 0.017 秒)

    RECOMBINANT PRRS PROTEINS, DIAGNOSTIC KITS AND VACCINES CONTAINING SAID RECOMBINANT PROTEINS
    91.
    发明公开
    RECOMBINANT PRRS PROTEINS, DIAGNOSTIC KITS AND VACCINES CONTAINING SAID RECOMBINANT PROTEINS 失效
    重组蛋白VIREN-PROTEINE在DIESELBENDIAGNOSESÄTZEUND IMPFSTOFFE ENTHALTENDEN

    公开(公告)号：EP0717108A1

    公开(公告)日：1996-06-19

    申请号：EP95917990.4

    申请日：1995-05-10

    申请人： CYANAMID IBERICA, SA

    发明人： PLANA DURAN, Juan ,  CASAL ALVAREZ, José Ignacio ,  CLIMENT SANCHEZ, Isabel

    IPC分类号： C12N15/40 ,  C07K14/08 ,  C12N7/01 ,  A61K39/12 ,  G01N33/569

    CPC分类号： C07K14/005 ,  A61K39/00 ,  C12N2710/14143 ,  C12N2770/10022 ,  Y10S424/815

    摘要： The present invention discloses the production of recombinant proteins of the virus causing the porcine respiratory and reproductive syndrome (PRRS), corresponding to the ORFs 2-7 of the PRRSV isolated in Spain, (PRRS-Olot), in a system of expression of recombinant baculoviruses multiplided in a cell culture of a permissive host. Said recombinant proteins are appropriate to formulate vaccines capable of efficiently protecting pigs against PRRS as well as to prepare diagnotic kits appropriate to detect both the presence of antibodies which recognize PRRSV and the presence of PRRSV in a porcine biological sample. This invention applies to veterinary.

    摘要翻译： 本发明公开了在重组表达系统中产生对应于在西班牙分离的PRRSV的ORFs 2-7（PRRS-Olot）的引起猪​​呼吸和生殖综合征（PRRS）的病毒的重组蛋白质的重组蛋白质 杆状病毒在允许宿主的细胞培养物中繁殖。 所述重组蛋白质适于配制能够有效保护猪免于PRRS的疫苗，以及制备适合于检测识别PRRSV的抗体的存在以及猪生物样品中PRRSV的存在的诊断试剂盒。 本发明适用于兽医。

    METHOD FOR DETECTING HEPATITIS E VIRUS INFECTION, AND ANTIGEN POLYPEPTIDE AND KIT FOR DETECTING HEPATITIS E VIRUS INFECTION
    98.
    发明公开
    METHOD FOR DETECTING HEPATITIS E VIRUS INFECTION, AND ANTIGEN POLYPEPTIDE AND KIT FOR DETECTING HEPATITIS E VIRUS INFECTION 审中-实审

    公开(公告)号：EP4372378A1

    公开(公告)日：2024-05-22

    申请号：EP22837658.8

    申请日：2022-07-05

    申请人： Advanced Life Science Institute, Inc.

    发明人： MAKI, Noboru ,  MORI, Kenichi ,  YAGI, Shintaro

    IPC分类号： G01N33/53 ,  C07K14/08 ,  C12N15/51 ,  G01N33/543 ,  G01N33/576

    CPC分类号： C07K14/02 ,  G01N33/53 ,  C07K14/08 ,  G01N33/576 ,  G01N33/543

    摘要： The present invention is a method for detecting hepatitis E virus infection, comprising a detection step of detecting anti-hepatitis E virus antibodies in a sample by using, as an antigen polypeptide, at least one polypeptide selected from the group consisting of the following (a) to (c):
    (a) a polypeptide consisting of an amino acid sequence which includes amino acids located at position 28 to 175 in the amino acid sequence set forth in any one of SEQ ID NOs: 1 to 4 and which has a full length of 200 residues or less that are contained in the amino acid sequence set forth in the sequence number;
    (b) a polypeptide consisting of an amino acid sequence in which one or more amino acids are substituted, deleted, inserted, and/or added in the amino acid sequence which includes amino acids located at position 28 to 175 in the amino acid sequence set forth in any one of SEQ ID NOs: 1 to 4 and which has a full length of 200 residues or less that are contained in the amino acid sequence set forth in the sequence number; and
    (c) a polypeptide consisting of an amino acid sequence having 80% or more homology with the amino acid sequence which contains amino acids located at position 28 to 175 in the amino acid sequence set forth in any one of SEQ ID NOs: 1 to 4 and which has a full length of 200 residues or less that are contained in the amino acid sequence set forth in the sequence number.