公开(公告)号：EP2295075A1

公开(公告)日：2011-03-16

申请号：EP10183730.0

申请日：2002-01-03

申请人： UNIVERSITY OF SASKATCHEWAN ,  UNIVERSITY OF BRITISH COLUMBIA

发明人： Finlay, Brett ,  Potter, Andrew

IPC分类号： A61K39/108 ,  C07K14/245 ,  C12N1/20 ,  A61P31/04 ,  A61K39/39 ,  C07K1/02

CPC分类号： A61K39/0258 ,  A61K2039/55566 ,  C07K14/245 ,  Y02A50/474

摘要： Compositions and methods for stimulating an immune response against a secreted enterohemorragic Escherichia coli (EHEC) antigen are disclosed. The compositions comprise EHEC cell culture supernatants.

摘要翻译： 公开了用于刺激针对分泌的肠道大肠杆菌（EHEC）抗原的免疫应答的组合物和方法。 组合物包含EHEC细胞培养物上清液。

公开(公告)号：EP2262914A1

公开(公告)日：2010-12-22

申请号：EP09714621.1

申请日：2009-02-27

申请人： University of Saskatchewan

发明人： GRAHN, Bruce ,  SANDMEYER, Lynne ,  FORSYTH, George ,  BELLONE, Rebecca

IPC分类号： C12Q1/68 ,  G01N33/53 ,  G01N33/68 ,  C07K14/705

CPC分类号： G01N33/6872 ,  C12Q1/6827 ,  G01N2800/16

摘要： The present application describes biomarkers and methods useful for screening for, diagnosing or detecting congenital stationary night blindness in a subject. The present application also provides methods for selecting or detecting horse coat patterns.

公开(公告)号：EP2257303A1

公开(公告)日：2010-12-08

申请号：EP09710681.9

申请日：2009-02-12

申请人： University of Saskatchewan

发明人： GORDON, John, R.

IPC分类号： A61K38/20 ,  A61K38/16 ,  A61P11/00 ,  A61P29/00 ,  A61P35/00 ,  A61P9/10

CPC分类号： A61K38/2053

摘要： Described herein is the use of a modified human chemokine, GS-CXCL8(3-73)K11R/G31P or G31P in the treatment of a number of diseases or disorders, including but by no means limited to pulmonary disorders, inflammatory diseases and disorders, cancers and surgical/ischemia reperfusion applications.

公开(公告)号：EP2229403A1

公开(公告)日：2010-09-22

申请号：EP08863748.3

申请日：2008-12-22

申请人： University of Saskatchewan

发明人： REANEY, Martin J. ,  JIA, Yunhua ,  SHEN, Jianheng ,  SCHOCK, Cynthia ,  TYLER, Nancy ,  ELDER, Jim ,  SINGH, Sarabjeet

IPC分类号： C07K7/64 ,  A61K36/55 ,  A61K38/12 ,  C07K1/14 ,  C07K7/50 ,  C11B1/10 ,  C11B3/00 ,  A23D9/00

CPC分类号： A61K36/55 ,  A23D9/00 ,  A23D9/007 ,  A61K38/00 ,  C07K1/145 ,  C07K1/16 ,  C07K1/20 ,  C07K7/64 ,  C11B1/06 ,  C11B1/102 ,  C11B3/006 ,  C11B3/10

摘要： Methods for separation and recovery of individual cyclic peptides from plant materials, said method comprising the steps of: (a) extracting an oil from a plant material; (b) separating the extracted oil into a non-polar fraction and a polar fraction; (c) separation and recovery of cyclic peptides from the non-polar fraction, and (d) separation and recovery of cyclic peptides from the polar fraction. The methods are suitable for separation and recovery of individual cyclolinopeptides from flax seed oil. Individual cyclolinopeptides are useful for modulation physiological disorders associated with apoptosis. Modified flaxseed oils may be produced by commingling flaxseed oils absent cyclolinopeptides, with at least one cyclolinopeptide separated and recovered with the methods disclosed herein.

公开(公告)号：EP2225194A1

公开(公告)日：2010-09-08

申请号：EP08853591.9

申请日：2008-12-01

申请人： University of Saskatchewan

发明人： REANEY, Martin, J.T. ,  SHEN, Jianheng ,  SOVERAN, Douglas, W.

IPC分类号： C07C29/70 ,  B01J31/02 ,  C07C31/30 ,  C07C67/02

CPC分类号： C11C3/003 ,  B01J31/0212 ,  B01J2231/49 ,  B01J2531/11 ,  B01J2531/12 ,  B01J2531/13 ,  B01J2531/14 ,  C07C29/70 ,  C07C29/94 ,  C07C31/30 ,  C07C67/03 ,  C07C69/24 ,  C07C69/52

摘要： The present disclosure relates to a process for the production of a base complex catalyst comprising reacting a hydroxide base with a polyalcohol, under vacuum pressure, at a temperature in the range of about 60°C to about 220°C, wherein the mole ratio f the hydroxide base to the polyalcohol is greater than about 2:1.

摘要翻译： 本发明涉及一种制备碱络合物催化剂的方法，其包括在约60℃至约220℃的温度下，在真空压力下使氢氧化物碱与多元醇反应，其中摩尔比f 氢氧化物碱与多元醇的比例大于约2:1。

公开(公告)号：EP2145961A3

公开(公告)日：2010-04-14

申请号：EP09011668.2

申请日：1999-04-15

申请人： UNIVERSITY OF SASKATCHEWAN

发明人： Reddy, Police Seshidhar ,  Tikoo, Suresh Kumar ,  Babiuk, Lorne A.

IPC分类号： C12N15/86 ,  A61K38/00 ,  C07K16/00 ,  C07K14/03 ,  A61K39/00

CPC分类号： C12N15/86 ,  A61K48/00 ,  A61K2039/53 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/10322 ,  C12N2710/10343 ,  C12N2710/10362

摘要： The complete nucleotide sequence of the genome of porcine adenovirus type 3 (PAV-3) is provided. Methods for construction of infectious PAV genomes by homologous recombination in procaryotic cells are provided. Recombinant PAV viruses are obtained by transfection of mammalian cells with recombinant PAV genomes. The PAV-3 genome can be used as a vector for the expression of heterologous nucleotide sequences, for example, for the preparation and administration of subunit vaccines to swine or other mammals. In addition, PAV-3 vectors can be used for gene therapy and expression of heterologous polypeptides. PAV-3 genome sequences can also be used for diagnostic purposes, to detect the presence of PAV-3 DNA in a subject or biological sample.

摘要翻译： 提供了猪腺病毒3型（PAV-3）基因组的完整核苷酸序列。 提供了在原核细胞中通过同源重组构建感染性PAV基因组的方法。 通过用重组PAV基因组转染哺乳动物细胞获得重组PAV病毒。 PAV-3基因组可以用作表达异源核苷酸序列的载体，例如用于制备和施用猪或其他哺乳动物的亚单位疫苗。 另外，PAV-3载体可用于基因治疗和表达异源多肽。 PAV-3基因组序列也可用于诊断目的，以检测受试者或生物样品中PAV-3DNA的存在。

公开(公告)号：EP1094837B1

公开(公告)日：2009-12-23

申请号：EP99932831.3

申请日：1999-06-28

申请人： MERIAL ,  The Queen's University of Belfast ,  The University of Saskatchewan

发明人： ALLAN, Gordon, Moore ,  MEEHAN, Brian, Martin ,  ELLIS, John, Albert ,  KRAKOWKA, George, Steven ,  AUDONNET, Jean-Christophe, Francis ,  MCNEILLY, Francis

IPC分类号： A61K39/395 ,  C07K14/01 ,  C12N7/00 ,  C12N15/86

CPC分类号： C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55566 ,  A61K2039/70 ,  C12N7/00 ,  C12N2750/10022 ,  C12N2750/10034 ,  C12N2750/14322 ,  C12N2750/14334 ,  Y10S424/815 ,  Y10S435/81

公开(公告)号：EP2120990A1

公开(公告)日：2009-11-25

申请号：EP08714609.8

申请日：2008-02-14

申请人： University of Saskatchewan

发明人： OBAYAN, Adebola O.E. ,  MUTWIRI, George, Kiremu

IPC分类号： A61K38/05 ,  A61K31/198 ,  A61K47/38 ,  A61K47/42 ,  A61K9/107 ,  A61K9/52 ,  A61K9/70 ,  A61L31/14 ,  A61P41/00

CPC分类号： A61K38/05 ,  A61L31/16 ,  A61L2300/25 ,  A61L2300/62

摘要： Glutamine source formulations that have release profiles that provide for sustained release via intraperitoneal administration of glutamine reduces post-operative adhesion formation.

摘要翻译： 具有通过腹膜内施用谷氨酰胺提供持续释放的释放曲线的谷氨酰胺来源制剂减少术后粘连形成。

公开(公告)号：EP1071758B1

公开(公告)日：2009-10-28

申请号：EP99917515.1

申请日：1999-04-15

申请人： UNIVERSITY OF SASKATCHEWAN

发明人： REDDY, Police, Seshidhar ,  TIKOO, Suresh, Kumar ,  BABIUK, Lorne, A.

IPC分类号： C12N15/861

CPC分类号： C12N15/86 ,  A61K48/00 ,  A61K2039/53 ,  C07K14/005 ,  C12N7/00 ,  C12N2710/10322 ,  C12N2710/10343 ,  C12N2710/10362

公开(公告)号：EP1379671B1

公开(公告)日：2009-05-06

申请号：EP02712700.0

申请日：2002-03-27

申请人： UNIVERSITY OF SASKATCHEWAN

发明人： LIU, Qiang ,  TIKOO, Suresh, K. ,  WILLSON, Philip ,  BABIUK, Lorne, A.

IPC分类号： C12N15/86 ,  C12N7/00 ,  C12N5/10 ,  C07K14/075 ,  C12N15/34 ,  A61K39/12

CPC分类号： C07K14/005 ,  A61K2039/525 ,  C12N7/00 ,  C12N15/86 ,  C12N2710/10322 ,  C12N2750/10021 ,  C12N2750/10043 ,  C12N2750/10052

摘要： The present invention relates to methods for culturing circovirus and in particular, porcine circovirus. The present invention provides compositions and methods for culturing porcine circovirus in mammalian cells expressing mammalian adenovirus E1 function.