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11.发明公开Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors 有权2,4-二氨基嘧啶的稠合双环衍生物作为ALK和c-Met抑制剂
公开(公告)号：EP2684874A1
公开(公告)日：2014-01-15
申请号：EP13173365.1
申请日：2007-10-23
申请人： Cephalon, Inc.
发明人： Ahmed, Gulzar , Bohnstedt, Adolph , Breslin, Henry, Joseph , Burke, Jason , Curry, Matthew , Diebold, James, L. , Dorsey, Bruce , Dugan, Benjamin, J. , Feng, Daming , Gingrich, Diane, E. , Guo, Tao , Ho, Koc-Kan , Learn, Keith, S. , Lisko, Joseph, G. , Liu, Rong-Qiang , Mesaros, Eugen, F. , Milkiewicz, Karen , Ott, Gregory, R. , Parrish, Jonathan , Theroff, Jay, P. , Thieu, Tho, V. , Tripathy, Rabindranath , Underiner, Theodore, L. , Wagner, Jason, C. , Weinberg, Linda , Wells, Gregory, J. , You, Ming , Zificsak, Craig, A.
IPC分类号： C07D239/48 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14 , A61K31/495 , A61P35/00
CPC分类号： C07D239/48 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D413/12 , C07D417/12 , C07D417/14
摘要： The present invention provides a compound of formula I or II or a pharmaceutically acceptable salt form thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , A 1 , A 2 , A 3 , A 4 , and A 5 , are as defined herein. The compounds of formula I or II have ALK and/or c-Met inhibitory activity, and may be used to treat proliferative disorders.
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12.发明公开PROTEASOME INHIBITOR DELANZOMIB FOR USE IN THE TREATMENT OF LUPUS 审中-公开PROTEASOME抑制剂DELANZOMIB ZUR BEHANDLUNG VON LUPUS
公开(公告)号：EP2680858A1
公开(公告)日：2014-01-08
申请号：EP12712440.2
申请日：2012-03-02
申请人： Cephalon, Inc.
摘要： The present invention provides a method for treating lupus in a subject, comprising the step of administering to the subject Compound A.
摘要翻译： 本发明提供一种治疗受试者的狼疮的方法，包括给予本发明化合物A的步骤。
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公开(公告)号：EP2648728A2
公开(公告)日：2013-10-16
申请号：EP11846725.7
申请日：2011-12-06
申请人： Cephalon, Inc.
IPC分类号： A61K31/437 , A61K31/4196 , A61K31/496 , A61K31/495 , A61P17/00
CPC分类号： A61K31/496
摘要： The present invention provides a method for treating lupus in a subject, comprising the step of administering to the subject COMPOUND A
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公开(公告)号：EP1863452B1
公开(公告)日：2013-04-03
申请号：EP06718390.5
申请日：2006-01-13
申请人： CEPHALON, INC.
IPC分类号： A61K9/19 , A61K47/10 , A61K31/4184
CPC分类号： A61K31/4184 , A61K9/0019 , A61K9/19 , A61K47/10
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公开(公告)号：EP1720891B1
公开(公告)日：2012-11-07
申请号：EP05706789.4
申请日：2005-02-24
申请人： Cephalon, Inc.
发明人： ROCK, Michael, Harold , LOPEZ DE DIEGO, Heidi , CHRISTENSEN, Kim, Lasse , NIELSEN, Ole , BUUR, Anders , HOWELLS, Mark
IPC分类号： C07H19/23 , A61K31/7056 , A61P25/16
CPC分类号： C07H19/23 , C07D491/22
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16.发明公开PROTEASOME INHIBITORS AND PROCESSES FOR THEIR PREPARATION, PURIFICATION AND USE 审中-公开蛋白酶抑制剂和法来制造，清洗和使用
公开(公告)号：EP2516449A1
公开(公告)日：2012-10-31
申请号：EP10798930.3
申请日：2010-12-22
申请人： Cephalon, Inc.
IPC分类号： C07F5/02
摘要： The invention provides boronic esters of Formula (I) wherein R
1 , R
2 , R
3 , and R
4 are as described herein, and methods for the preparation and purification thereof.-
公开(公告)号：EP2516445A2
公开(公告)日：2012-10-31
申请号：EP10799203.4
申请日：2010-12-17
申请人： Cephalon, Inc.
发明人： BACON, Edward R. , BAILEY, Thomas R. , DUNN, Derek D. , HOSTETLER, Greg A. , MCHUGH, Robert J. , MORTON, George C. , ROSSE, Gerard C. , SALVINO, Joseph M. , SUNDAR, Babu G. , TRIPATHY, Rabindranath
IPC分类号： C07D491/048 , C07D491/20 , C07D513/04 , C07D491/153 , A61K31/4355 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P25/32 , A61P25/36
CPC分类号： C07D491/153 , C07D491/048 , C07D491/20 , C07D513/04
摘要： This application relates to tricyclic compounds of Formula (I), including all stereoisomers, mixtures of stereoisomers, and salts thereof. This application also relates to compositions comprising compounds of Formula (I) and uses therefore.
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公开(公告)号：EP1539126B1
公开(公告)日：2012-08-29
申请号：EP03749630.4
申请日：2003-09-12
申请人： CEPHALON, INC.
发明人： HEACOCK, Craig , PARIKH, Alpa , PATEL, Piyush, R.
IPC分类号： A61K31/165 , A61P25/00 , A61K9/20
CPC分类号： A61K9/2018 , A61K9/2027 , A61K9/2054 , A61K31/165
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19.发明授权COMBINATION OF THE ANALEPTIC MODAFINIL AND AN ANTIDEPRESSANT FOR THE TREATMENT OF DEPRESSION 有权Analeptikum莫达非尼与治疗抑郁症的抗抑郁药组合
公开(公告)号：EP1628652B1
公开(公告)日：2012-07-11
申请号：EP04761006.8
申请日：2004-05-13
申请人： CEPHALON, INC.
IPC分类号： A61K31/343 , A61K31/165 , A61K31/138 , A61K31/4525 , A61P25/24
CPC分类号： A61K31/165 , A61K31/138 , A61K31/343 , A61K31/4525 , A61K2300/00
摘要： Compositions and methods for treatment of depressive disorders through the administration of modafinil with antidepressants.
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20.发明授权SUBSTITUTED SPIROCYCLIC PIPERIDINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS 有权取代的螺环哌啶衍生物比组胺-3（H 3）受体的配体
公开(公告)号：EP2257553B1
公开(公告)日：2011-08-31
申请号：EP09706445.5
申请日：2009-01-28
申请人： Cephalon, Inc.
IPC分类号： C07D491/10 , A61K31/501 , A61P25/00
CPC分类号： C07D491/113 , C07D491/10 , C07D491/107
摘要： The present invention provides compounds of Formula (I): their use as H3 antagonists/inverse agonists, processes for their preparation, and pharmaceuticals compositions thereof.
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